aging

From stem cell-recruiting gels to hormone cycle restoration, Tracy Criswell has big ideas about how to combat age-related decline in muscle regeneration.

Biogerontologist Matt Kaeberlein studies aging pets to determine how to improve healthspan in dogs and their humans.

Yeast cells share metabolites through extracellular space to extend the lifespan of the entire community.

Alysson Muotri launched brain organoids into outer space and found that microgravity enriches our understanding of brain development and disease.

Neuroscientists developed and tested a promising mobile app that mitigates age-related memory decline.

Aging cells with weakened gene regulation spuriously transcribe RNAs, but their impact on health and longevity still needs to be examined.

The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.

Senescent cells undergo major morphological and metabolic changes when at the end of their lifespan. 

Researchers learned how IGFBP7, a senescence signaling protein and biomarker, promotes cardiac remodeling and cellular aging.

By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.

Repairing damaged DNA appears to drive aging by causing the loss of epigenetic information, but restoring that information reverses such effects, a study finds.

Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline. 

Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms. 

Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.

Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.

Researchers say there may be similar, human genes whose effects on lifespan vary by sex.

Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.

Researchers caution that it’s too soon to recommend supplements based on the results of a new study.

Researchers say they've figured out how some reproductive ants live up to 30 years—far longer than workers.

The Middlebury College neuroscientist explores enzymes that affect brain cell development and neurodegeneration.