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An illustration showing a DNA strand and a cancer cell.
How Some Cancer Cells Survive Chemotherapy
Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells overcome this effect and resist death. 
How Some Cancer Cells Survive Chemotherapy
How Some Cancer Cells Survive Chemotherapy

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells overcome this effect and resist death. 

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells overcome this effect and resist death. 

apoptosis

A small furry shrew pokes its head out from a pile of vegetation.
Gene Expression Shifts as Shrews Shrink and Regrow Their Brains
Hannah Thomasy, PhD | Nov 20, 2024 | 5 min read
Transcriptomic studies of the shrew’s remarkably plastic brain could provide new insights into neurodegenerative diseases.
Discover How Automated Microscopy Streamlines Multiplexed Apoptosis Assays
Multiplexing Caspase-Based Apoptosis Assays with Automated Microscopy 
Leica Microsystems | May 29, 2024 | 1 min read
A state-of-the-art automated microscope streamlines data acquisition and analysis for multiplex assays.
A cell undergoing programmed cell death with internal components leaking out
Programmed Cell Death
The Scientist | Mar 4, 2024 | 1 min read
Multicellular organisms can self-destruct their cells through a variety of mechanisms.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Fluorescently labeled neuron cell bodies in blue in the center compartment of a three-compartment microfluidic chamber grow through tiny grooves to enter the left and the right chambers, where they extend axons fibers, also shown in blue.
Visualizing Axon Pruning
Tiffany Garbutt, PhD | Oct 2, 2023 | 2 min read
During development, neurons trim hundreds of excess axons in an intricately coordinated destructive process.
Cell division abstract image
Versatile and Sustainable: Cell Counting for the 21st Century
The Scientist and DeNovix Inc. | Mar 23, 2023 | 3 min read
Discover how the latest cell counting technology is reshaping a mundane task for the future.
Programmed Cell Death: Mechanisms for Cellular Self-Destruction
Programmed Cell Death Pathways
Elina Kadriu | Feb 15, 2023 | 7 min read
Cells use a variety of programmed cell death mechanisms to maintain homeostasis through cellular self-destruction, including apoptosis, necroptosis, and pyroptosis.
Infographic preview
Infographic: A Brain Implant Stops Tumor Growth in Rats
Holly Barker, PhD | Dec 12, 2022 | 1 min read
The new, implantable device converts ultrasound waves into electrical energy inside the brain, interfering with tumor cell division.
Render of cancer cells
Implantable Device Zaps Cancer Cells Using Electric Fields
Holly Barker, PhD | Dec 12, 2022 | 3 min read
A wireless brain implant inhibits tumor growth in rats, overcoming many design flaws of current devices used to treat glioblastoma.
Explore How Microplate-Based Cellular Assays Advance Life Science Research
Elevate Cellular Assays with Microplate Readers
BMG LABTECH | Dec 1, 2022 | 1 min read
Scientists combine microplate readers and cell-based assays for high throughput and reduced variability across a variety of applications.
A colored microscopy image showing cells that are dying in yellow and healthy cells in blue 
Sweet Taste Receptors Regulate Proteins in Developing Fruit Flies
Tess Joosse | Nov 14, 2022 | 2 min read
An unexpected find shows that sweet-sensing receptors also help epithelial cells in Drosophila larvae stay alive amid proteotoxic stress.
Illustration of two weaving proteinsĀ 
Fusion with Spider Silk Increases Anticancer Protein’s Stability
Dan Robitzski | Jul 5, 2022 | 2 min read
Scientists found that combining the notoriously flimsy anticancer protein p53 with a domain from a spider silk protein resulted in a more stable hybrid that’s more potent and easier for cells to synthesize.
A drawing of pseudostratified gut epithelial cells in the early intestines, cells in red and nucleus in purple.
Move Over Apoptosis: Another Form of Cell Death May Occur in the Gut
Natalia Mesa, PhD | May 18, 2022 | 6 min read
Though scientists don’t yet know much about it, a newly described process called erebosis might have profound implications for how the gut maintains itself.
line illustration of DNA with single-strand break
Cancer Cells Break Own DNA to Defend Against Radiation
Sophie Fessl, PhD | Apr 28, 2022 | 3 min read
Self-inflicted DNA breaks let the cells hit pause on repair of radiation-induced DNA damage, giving them time to recover, an in vitro study shows.
Dark red cancer cells travel through the circulatory system alongside small, brighter-colored red blood cells
Traversing Narrow Channels Helps Metastatic Cancer Cells Survive
Dan Robitzski | Apr 14, 2022 | 4 min read
In vitro and mouse experiments show how cancer cells forced through tiny pores—mimicking the physical experience of metastasis—resisted programmed cell death and avoided detection by the immune cells that would normally kill them.
Diffuse star-like shapes with regions in purple, green, and both colors overlapped.
Tumor Cells on Brink of Death May Trigger Metastasis
Alejandra Manjarrez, PhD | Mar 25, 2022 | 5 min read
A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body.
Image of fruit fly epithelial cells (pseudo colored in this micrograph)
Epithelial Cell Signaling Helps Maintain Tissue Integrity
Annie Melchor | Nov 1, 2021 | 2 min read
Using a transgenic fruit fly model, researchers demonstrate how epithelial barriers are maintained in living organisms despite high levels of cell turnover and death.
Discover how to scale up cellular assays during drug discovery
High-Throughput Solutions for Lead Candidate Discovery
The Scientist and Thermo Fisher Scientific | Oct 18, 2021 | 1 min read
New technologies allow researchers to scale up assays for cellular functions.
Discover the In-Cell Western Assay
Detecting Proteins in Their Native Environments
LI-COR | Sep 14, 2021 | 1 min read
A quantitative immunofluorescence assay combines the best aspects of traditional Western blots and ELISAs.
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