The Neural Circuitry Driving Cancer-Related Wasting Disease
The Neural Circuitry Driving Cancer-Related Wasting Disease
In mice, dampening the activity of area postrema neurons diminished cancer-induced muscle and fat loss and increased lifespan.
In mice, dampening the activity of area postrema neurons diminished cancer-induced muscle and fat loss and increased lifespan.
cachexia
Cachexia Is Driven By Killer T Cells in a Mouse Model of Infection
Katarina Zimmer | May 22, 2019 | 5 min read
A new study reveals an unexpected role for the immune cells and a previously unknown mechanism for the wasting syndrome.
Insulin Interference Triggers Cancer-Linked Cachexia
Jyoti Madhusoodanan | Apr 6, 2015 | 3 min read
A tumor-secreted protein interferes with insulin signaling to cause cancer-linked muscle wasting in fruit flies.
Flipped Fat-burning Linked to Cancer Cachexia
Jyoti Madhusoodanan | Jul 22, 2014 | 2 min read
Conversion of white fat to brown is associated with muscle atrophy and weight loss in cancer patients.