cell & molecular biology

Researchers identified a novel mechanism by which chemically induced stress is “remembered” by the mitochondria of worms more than 50 generations after the original trigger.

By viewing countless hours of expectorating worms, researchers discover a unique way in which neurons control the movement of muscles.

Immunologists and parasitologists are working to revive the idea that helminths, and more specifically the molecules they secrete, could help treat allergies and autoimmune disease.

Research in animals and people supports a range of mechanisms by which the parasites affect physiology and immune responses.

Neurons stressed with chemicals produce Wnt, which in turn triggers changes in the germline.

A technique that reversibly bundles tagged cargo into artificial membraneless compartments gives scientists the ability to switch cell processes on and off.

Engineered cells produce proteins that allow scientists to turn cellular processes on and off.

Liquid conglomerations of molecules that form in bacterial cells in response to stress promote the cells’ survival, a study finds.

Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.

The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

The methodology involves modifying histones and displaying them on the cell surface for analysis.

By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.

Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.

The AlphaFold program from AI firm DeepMind has amassed a huge database of protein structures from humans and model organisms.

Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples.

The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol.

A study of 19 postmenopausal women found that eating a bar of chocolate in the morning affected their bodies differently than eating it at night, but neither led to weight gain.

Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?

After receiving an intraocular injection of the gene for a light-sensitive protein, a 58-year-old man diagnosed with the neurodegenerative eye disease retinitis pigmentosa was able to locate objects on a table using engineered goggles.