cell signaling

New technologies allow researchers to scale up assays for cellular functions.

Explore how researchers use cryogenic electron microscopy (cryo-EM) to identify how mutations affect protein signaling and function through structural or conformational changes.

Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.

Researchers have identified specific cells and neuropeptides involved in mediating the sneeze response in mice exposed to allergens or chemical irritants such as capsaicin.

The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.

A mouse study identifies the brain regions and specific signaling factors that regulate the sneeze response.

Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?

Prior to a 2019 preprint, “glycoRNAs” weren’t known to exist. Now, the researchers who found them say they’re on lots of cells and may play a role in immune signaling.

Corticosterone interferes with signaling in the skin that normally activates hair follicle stem cells, possibly explaining the link between stress and hair loss.

Recent insights, such as the recognition that disseminated cancer cells can lie dormant for years before seeding secondary tumors, suggest novel strategies for fighting metastatic disease.

Surveillance Gaps: How Cancer Arises

A tumor metabolome panel identifies altered cell states that lead to drug tolerance.

Discover how scientists use multi-omic approaches to identify functional changes that lead to cancer cell drug resistance and devise new treatment strategies.

In two independent studies, researchers find that the organelle is responsible for a switch that allows cells to start moving when they’re squeezed.

Molly Shoichet and Bridget Wagner discuss strategies for using phenotypic screening to identify novel agents against diseases such as cancer and diabetes.

Best known as a cell cycle regulator, p53 signaling mediates pro and anti-cancer immune responses as well

Presenters in this webinar will discuss how cancer not only evades the immune system, but also co-opts it to promote tumor growth.

Download this research summary to learn about how single-cell proteomics and metabolomics methods unlock drug resistance mechanisms!

Human embryonic stem cells differentiate and organize themselves on a chip.

Numerous cellular changes underlie the decline of muscle mass and strength in the elderly.