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A pink and yellow protein held together by a gray circle pulls a piece of blue DNA into a loop.
Combining Bacterial Systems Offers a New Approach to Gene Regulation
Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression.
Combining Bacterial Systems Offers a New Approach to Gene Regulation
Combining Bacterial Systems Offers a New Approach to Gene Regulation

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression.

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression.

DNA

3D illustration of an antibody bound to a metallic nanoparticle.
A New Approach Improves Signal Detection in Mass Cytometry
Shelby Bradford, PhD | Oct 24, 2024 | 3 min read
A team of researchers developed a technique, ACE, to improve the ability to study low-abundance proteins using mass cytometry.
Discover the Advantages of Saliva Samples as a Source of Total Nucleic Acids.
Total Nucleic Acid Sample Collection Saliva Solutions for Host and Microbial Applications
DNA Genotek Inc. | Oct 1, 2024 | 1 min read
Examining the advantages of saliva samples for genomics and microbiome researchers as a source of total nucleic acids. 
A wooded ecosystem with mammoths alongside modern species such as arctic hares
Scientists Unearth the Oldest DNA Ever Found
Katherine Irving | Sep 27, 2024 | 3 min read
The 2.4-million-year-old environmental DNA fragments collected from permafrost in northern Greenland unlock insights into an ancient ecosystem.
Conceptual image of hands wearing surgical gloves holding a test tube filled with a liquid biopsy sample.
Enhanced Sequencing Results from Liquid Biopsies
The Scientist Staff | Sep 16, 2024 | 2 min read
Using a library preparation kit optimized for cell free DNA (cfDNA) provides high quality data for early cancer detection.
A row of PCR tubes with clear liquid inside.
Introducing More Flexibility to Automated Liquid Handling
The Scientist Staff | Aug 1, 2024 | 2 min read
The latest automated liquid handling robots are adaptable to numerous techniques for sample extraction, isolation, and purification. 
Discover the benefits of a cfDNA library preparation workflow aimed to improve cfDNA sequencing sensitivity.
Improving cfDNA Sequencing Sensitivity by Optimizing Library Preparation
Twist Bioscience | Jul 3, 2024 | 1 min read
Explore a cfDNA library preparation workflow that maximizes sensitivity and conversion with low sample inputs.
A digital graphic rendering of multiple DNA double helices on a white background.
Targeted Gene Integration for High-Throughput Applications
Nathan Ni, PhD | Jun 20, 2024 | 4 min read
A new approach using two types of recombinases lets scientists insert larger DNA payloads into human pluripotent stem cells faster than ever before. 
A light blue circular double helix against a dark blue background.
Artificial Chromosomes for Disease Modeling
Holly Barker, PhD | Jun 12, 2024 | 3 min read
A new technique for synthesizing chromosomes can introduce panels of genes into disease models to facilitate drug testing.
3D illustration of purple neurons.
An Immune Mechanism Maintains Memory
Shelby Bradford, PhD | Jun 10, 2024 | 4 min read
A receptor that recognizes DNA fragments formed during learning is necessary for proper memory formation.
Discover How Water Quality Affects Reproducibility for Genetics and Genomics Research
High-Purity Reagents Ensure Reproducibility for Genetics and Genomics Research 
ELGA Veolia | Apr 9, 2024 | 1 min read
Used across a wide range of techniques and methods, water quality has a pivotal role in genetics and genomics research.
Discover a Saliva Collection Device for Multi-Omic Research.
Capturing Total Nucleic Acids from Saliva Samples for Multiomics Applications
DNA Genotek Inc. | Mar 25, 2024 | 1 min read
Saliva is a viable alternative source of nucleic acids. A new collection device offers stable and easy saliva collection for extracting both DNA and RNA from a single sample.  
Abstract blue color digital particles wave with dust and light background.
Predict Functional Genomics with Confidence
The Scientist Staff | Mar 1, 2024 | 1 min read
An advanced multiomics solution allows researchers to predict gene expression, chromatin accessibility, and enhancer state from one DNA sample.
Graphic of three double-stranded DNA helices with bases colored yellow, light green, blue, and dark blue
ABC Sequencing Helps Scientists Get Back to Basics
Element Biosciences | Feb 16, 2024 | 1 min read
A novel instrument simplifies and optimizes every sequencing step.
A man with glasses that looks distressed as he stands in front of a laboratory bench with his failed experiment.
Voltage Ventured, Nothing Gained
Laura Tran, PhD | Feb 1, 2024 | 2 min read
A common mistake and a well intentioned but misguided gesture led Allison Mackay’s experiment awry in the lab.
Infographic showing how recombinase polymerase amplification (RPA) technique works.
Infographic: Recombinase Polymerase Amplification in Action
Hannah Thomasy, PhD | Dec 4, 2023 | 4 min read
A rapid isothermal amplification technique enables pathogen identification and antibiotic resistance detection in low-resource settings.
Eytan Stibbe wears a headset and a blue shirt while surrounded by computers and other equipment on the International Space Station.
Whenever, Wherever: Taking DNA Amplification Outside the Lab
Hannah Thomasy, PhD | Dec 4, 2023 | 10 min read
Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.
Samantha Maragh speaks on stage after receiving the State of Maryland Outstanding Young Scientist Award 2019.
Making Standards Exceptional
Meenakshi Prabhune, PhD | Dec 4, 2023 | 9 min read
Samantha Maragh has taken on the difficult challenge of standardizing assays, data norms, and terminology in the ever evolving genome editing field.
A blood test tube with the label ‘cfDNA Screening–Test’, held in a hand wearing blue gloves.
The Basics and Applications of Cell-Free DNA 
Rebecca Roberts, PhD | Nov 8, 2023 | 5 min read
Found circulating in peripheral blood, scientists use cell-free DNA (cfDNA) to assess genetic abnormalities, infections, cancer, transplant rejection, and cardiovascular disease.
qPCRDriving Wastewater Surveillance for Infectious Disease
Nathan Ni, PhD | Oct 30, 2023 | 3 min read
Natalie Knox and the Public Health Agency of Canada’s National Microbiology Laboratory are helping establish a national qPCR-driven wastewater surveillance network for SARS-CoV-2 and other diseases.
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