drug toxicity

Cellular immunogenicity and immunotoxicity assays help scientists design, validate, and translate therapeutic research into treatments that weaponize the immune response against cancer.

Discover how cutting-edge nonclinical in vitro models better recapitulate the human gastrointestinal tract.

New flow imaging microscopy technology visualizes a broad range of subvisible particles hidden in therapeutic suspensions.  

Machine learning could be the key to reducing the use of animals in experiments.

Researchers develop a machine-learning tool for toxicity analyses that is more consistent in predicting chemical hazards than assays on animals.

Biotech stocks fell in response to the news. 

Scientists debut a system that can quickly test the toxicity of thousands of compounds in vitro.

Weight-loss drugs that target newly characterized obesity-related receptors and pathways could finally offer truly effective fat control.

Investigational drug that inhibits proteins involved with epigenetic regulation shows activity against certain blood cancers in an early-stage clinical trial.

A pro-pot group airs an ad stating marijuana is “less toxic” than alcohol, but a federal science agency disputes the assertion.

A mass poisoning of 105 patients treated with an untested medication spurred Congress to empower the US Food and Drug Administration to monitor drug safety.

Results of breast cancer drug trials are regularly spun to conceal bias and make the drugs seem more effective or less toxic than they really are.

Affordable diagnostic tests tackle the world’s most pressing health problems.

How to screen for toxicity using stem cells

The National Institutes of Health will fund 17 projects developing lab-on-a-chip applications to improve drug screening.

Rodents fed all-you-can-eat diets may be skewing experimental results.

A novel antibody with a powerful affinity for cocaine shows promise in reversing the deadly effects of an overdose.

Advances in cell-culture technologies are paving the way to the complete elimination of animals from the laboratory.

The NIH, FDA, and DARPA are teaming up to develop a chip to test drug toxicities as one of the first projects of the NIH's new translational research center.