epigenetics

The epigenome regulates nearly every process in the human body. By studying epigenetics, scientists have revealed some secrets to aging, cancer, and complex diseases.

Gut microbiome disruption in male mice increases disease risk in offspring, indicating that preconception paternal health status can affect the next generation.

Instead of an on-off toggle switch, cancer cells adapt through a series of distinct states of increasing drug resistance.

In this webinar, Austin Holmes and Jason Koth will discuss how to overcome single cell methylation and data analysis hurdles.

A protein in natural killer cells keeps them from turning into more docile counterparts.

A lower-resolution spatial epigenomics method offers a cost-effective alternative to traditional single-cell approaches.

When it comes to development, an epigenetic clock may be responsible for human neurons’ slower maturation.

Modifying markers on DNA allows scientists to lower cholesterol levels in mice, even long-term.

Profiling genetic variants and DNA methylation changes in cell free DNA could transform the detection of cancers including hepatocellular carcinoma.

A multiomic sequencing approach helps scientists capture more biomarker information through liquid biopsy.

To gather multiomic insights, researchers used to combine data from multiple workflows, but duet evoC provides more information from less sample in one workflow.

An advanced multiomics solution allows researchers to predict gene expression, chromatin accessibility, and enhancer state from one DNA sample.

Jonathan Weissman and Luke Gilbert share how they developed several CRISPR-based epigenetic editors and how these tools differ from traditional CRISPR.

In this webinar, Özgen Deniz and Christina Leslie will discuss how epigenetic regulation affects oncogenesis.

An analysis of almost 700 different tumors revealed that DNA methylation drives tumorigenesis just like genetic mutations do. 

A new strategy prevents reprogramming-induced epigenetic aberrations in human induced pluripotent stem cells.

Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.

How will a new version of epigenetic clocks aimed at validating the age of people older than 100 years of age balance accuracy and anonymity?

Scientists present the latest research on immune cell responses to cancer, the role of epigenetics in cancer, and molecular imaging of the tumor microenvironment.