exercise

Altering DNA methylation in a particular area of the hypothalamus halved the animals’ voluntary exercise as adults.

Men had better fat-burning results when they had breakfast after cycling instead of beforehand.

New, unpublished results show some of the cells produce new neurons for up to 90 days, much longer than a previously identified set of neural stem cells that only generate neurons for a month or two.

Physical activity, independent of diet, shifts the composition of bacteria in the intestines, spurring researchers to search for species that might provide benefits akin to working out.

A mouse study finds that when blood platelets are activated during exercise, they release factors that increase the number of newborn neurons in the hippocampus.

From cellular self-digestion to the effects of exercise on the brain, our features editor picks her favorite art custom-made for the magazine.

They hope to develop the “exercise hormone” into therapeutics that harness the benefits of exercise for people unable to do so.

Identifying the molecular interactions that occur all over the body during exercise could reveal how it affects learning and memory.

As researchers unravel the molecular machinery that links exercise and cognition, working out is emerging as a promising neurotherapy.

Boosting both neurogenesis and a brain-derived growth factor can mimic the cognitive benefits of exercise in a mouse mode of Alzheimer’s disease.

Directly activating a heat sensor also sensitive to capsaicin in chili peppers in the hypothalamus had the same effect as exercise.

Epinephrine’s activation of the signaling pathway Hippo is responsible for the in vitro tumor-fighting effects of serum from women who worked out.

Male rodents given access to a running wheel early in life show increased neural activity and improved memory as adults.

Researchers at the Society for Neuroscience discuss what we know—and don’t—about how physical activity affects the brain.

Endurance exercise and metabolism are linked to transcriptional activation of human telomeres, researchers propose.

Running releases an enzyme that is associated with memory function in mice and humans.
 

At the American Association for Cancer Research annual meeting, researchers review the evidence that exercise has antitumor benefits.

Leptin, the satiety hormone produced by fat, affects neuronal signaling in the mouse brain; interference with this pathway can influence the rewarding effects of running in the animals.

Researchers who first identified irisin quantitate levels of the hormone in human blood and show it is released during exercise.  

Following extreme trauma, patients’ adipose samples have revealed—for the first time in humans—that white fat can be converted into energy-burning brown fat.