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Crystal structure of adeno-associated virus serotype 3B
A Deep Dive into Viral Vectors for Gene Therapy 
As the demand for viral vectors rises in new gene therapy approaches, scientists seek ways to optimize their production.
A Deep Dive into Viral Vectors for Gene Therapy 
A Deep Dive into Viral Vectors for Gene Therapy 

As the demand for viral vectors rises in new gene therapy approaches, scientists seek ways to optimize their production.

As the demand for viral vectors rises in new gene therapy approaches, scientists seek ways to optimize their production.

gene editing

Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids
Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids
The Scientist Staff | Oct 16, 2024 | 1 min read
In this webinar, Cole Cheng and Connie Rich will discuss the advantages of novel miniaturized plasmids for streamlining preclinical and clinical gene therapy development.
Blue and pink DNA helix and human lungs on a blue background.
Nanoparticles Breathe New Life into Lungs
Sneha Khedkar | Oct 15, 2024 | 4 min read
Lipid nanoparticles deliver CRISPR tools directly to lung stem cells, offering new therapeutic avenues for treating genetic diseases.
Image of the small intestines and colon within a person with three circular callouts, highlighting different microbes. 
Unlocking the Human Microbiome Mysteries: From Cancer to COVID-19
Laura Tran, PhD | Sep 24, 2024 | 4 min read
The microbiome is a dynamic environment that can give researchers the inside scoop on health and disease.
A conceptual illustration of scissors, which represents a CRISPR-Cas9 complex, cutting a DNA molecule.
Cell Engineering 101: Editing with CRISPR
EditCo | Sep 23, 2024 | 1 min read
Discover how scientists produce CRISPR-edited cell populations.
Two hands holding tweezers and dissecting single points in a DNA sequence.
From CRISPR to Prime Editing: The Evolution of the Genome Editing Revolution
Danielle Gerhard, PhD | Sep 17, 2024 | 5 min read
Even as CRISPR-based tools become a lab staple, scientists strive to tackle the associated technological challenges to improve their efficacy and safety.   
Optimizing Gene Editing Experimental Design
Optimizing Gene Editing Experimental Design
The Scientist Staff | Aug 26, 2024 | 1 min read
In this webinar, Jacob Lamberth will discuss the critical variables and strategies for revolutionizing gene editing experiments.
Conceptual vector image of scientist engage in molecular biology research.
Helper Plasmids Lend a Hand to AAV Production
Sartorius and Polyplus | Aug 21, 2024 | 1 min read
An innovative helper plasmid improves adeno-associated virus quality and infectivity.
Twist
Synthetic Screens, Genes, and De Novo Proteins - A Special Podcast Series
The Scientist and Twist Bioscience | Aug 8, 2024 | 2 min read
In this podcast series, scientists discuss the unique ways they employ synthesized DNA libraries in their research. 
Dark blue RNA strands with a light blue background.
A CRISPR Tool for Tinkering with the Human Transcriptome
Danielle Gerhard, PhD | Jul 23, 2024 | 5 min read
Human cells repair RNA breaks induced by a programmable CRISPR system, paving the way for temporary treatments for genetic diseases.
Discover What Digital PCR Can Do Across a Wide Range of Applications
Digital PCR Applications
Thermo Fisher Scientific | Jul 9, 2024 | 1 min read
Digital PCR is highly sensitive and precise, making it ideal for detecting rare targets and measuring small-fold changes.
A digital graphic rendering of multiple DNA double helices on a white background.
Targeted Gene Integration for High-Throughput Applications
Nathan Ni, PhD | Jun 20, 2024 | 4 min read
A new approach using two types of recombinases lets scientists insert larger DNA payloads into human pluripotent stem cells faster than ever before. 
Molecular illustration of CRISPR editing the DNA double helix
Prime Time Precision with CRISPR Technologies
The Scientist | Apr 29, 2024 | 1 min read
Base editors and prime editors help researchers perform more precise in vivo and ex vivo translational research.
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
All Roads Lead to Genome Editing
Danielle Gerhard, PhD | Feb 9, 2024 | 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
Twisted DNA Increases CRISPR Off-target Effects
Shelby Bradford, PhD | Feb 8, 2024 | 4 min read
Understanding how Cas9 binds off-target sequences can help researchers refine CRISPR-mediated genome editing.
Avoiding Gene Editing’s Unintended Consequences
Tanvir Khan, PhD | Feb 2, 2024 | 4 min read
CRISPR-Cas9 editing leads to widespread loss of the targeted chromosome in human T cells, but scientists recently discovered a way to prevent such loss.
Conceptual vector illustration depicting CRISPR gene editing by scientists for medical applications.
Optimizing Gene Editing with PARP1 CRISPR Plasmids 
The Scientist and Santa Cruz Biotechnology, Inc. | Jan 24, 2024 | 3 min read
CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.   
Blood vessel with flowing red blood cells and white immune cells.
New CRISPR Treatment Could Prevent HIV Reinfection after Viral DNA Excision
Jennifer Zieba, PhD | Aug 21, 2023 | 3 min read
Researchers design dual CRISPR treatments to remove HIV DNA and prevent reinfection in vitro.
Photo of Rosa Bacchetta, associate professor of pediatrics at Stanford University
The Future of Gene Therapy for a Rare Pediatric Autoimmune Disease
Niki Spahich, PhD | Jul 10, 2023 | 3 min read
By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.
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