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An illustration of seven T cells (in seafoam green) attack a cancer cell (in pink).
Meet Cyclone: A Monitoring Tool That Watches for Waves of Immune Response
A new algorithm detects when immunotherapies create surges of T cell responses in melanoma patients.
Meet Cyclone: A Monitoring Tool That Watches for Waves of Immune Response
Meet Cyclone: A Monitoring Tool That Watches for Waves of Immune Response

A new algorithm detects when immunotherapies create surges of T cell responses in melanoma patients.

A new algorithm detects when immunotherapies create surges of T cell responses in melanoma patients.

melanoma

An illustration of a single cancer cell (in seafoam green) with four white blood cells (in green) attached to it.
The Circadian Clock Tells the Right Time for Immunotherapy
Sahana Sitaraman, PhD | Sep 23, 2024 | 4 min read
Administering immunotherapy when the tumor microenvironment is most susceptible to T cells enhances treatment efficacy in mice.
A melanoma on human skin.
Minicells Shut Down Cancer’s Spread 
RJ Mackenzie | Jul 29, 2024 | 4 min read
A nutrient-based nanomedicine stopped runaway tumor growth in mice by firing up a latent metabolic pathway.
Beyond Skin Deep: Analyzing Melanoma Cells Through Morphology
Beyond Skin Deep: Analyzing Melanoma Cells Through Morphology
The Scientist | Nov 7, 2023 | 1 min read
In this webinar, Evelyn Lattmann will discuss how she examined melanoma cell morphology without labels using an AI-based microscope system.  
Mega Multiplexing for Exploring Diseased Tissues
Niki Spahich, PhD | Oct 16, 2023 | 4 min read
Researchers at KU Leuven specialize in performing a multiplex immunohistochemistry method that uses conventional antibodies and pathologist-driven data analysis.
A drawing of the sun on the sand, surrounded by items that people use to protect themselves from UV damage, including sunscreen, a hat, and sunglasses.
Taking Snapshots of DNA Damage in Skin Cancer
Deanna MacNeil, PhD | Aug 15, 2023 | 3 min read
Researchers turn to high resolution sequencing to explain recurrent melanoma mutations caused by UV exposure.
<em >The Scientist</em>&rsquo;s Journal Club: Cancer
The Scientist’s Journal Club: Cancer
The Scientist | Jun 23, 2023 | 1 min read
Scientists present the latest research on immune cell responses to cancer, the role of epigenetics in cancer, and molecular imaging of the tumor microenvironment.
illustration of T cell attached to protein
“Smarter” CAR T Cells Target Tumors with Precision
Natalia Mesa, PhD | Dec 16, 2022 | 5 min read
Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.
Grayscale microscopic image of dying melanoma cells
Science Snapshot: Living Bubble Wrap
Lisa Winter | Oct 5, 2022 | 1 min read
This year’s fourth-place winner of the 2022 Nikon Small World in Motion competition shows dying melanoma cells.
Salmonella (pink) invading a human epithelial cell (yellow)
Modified Salmonella Revs Immune Response, Combats Tumors in Mice
Natalia Mesa, PhD | Feb 3, 2022 | 5 min read
When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.
Discover how biobanking accelerates cancer research
On the Path to Personalized Medicine
Thermo Fisher Scientific | Dec 3, 2021 | 1 min read
Scientists combine medical care with biobanking and research to develop personalized treatments for cancer patients.
A false-colored micrograph showing swirls of yellow, red, and magenta cells
Cross-Resistance: One Cancer Therapy Can Undermine the Next
Sophie Fessl, PhD | Jul 16, 2021 | 6 min read
Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples.
An illustration of several DNA helices on a light red water color background
Human Blood Harbors Cell-Free Microbial DNA
Abby Olena, PhD | Jul 9, 2021 | 3 min read
After controlling for high levels of bacterial contamination in their lab and reagents, researchers detect microbial genetic material in plasma samples from healthy people and cancer patients.
a leopard gecko with an unusually yellow body
“Lemon Frost” Leopard Geckos’ Cancers Similar to Human Melanomas
Christie Wilcox, PhD | Jun 24, 2021 | 6 min read
The color morph’s bright yellow hue and its propensity for skin tumors both likely stem from a gene implicated in a dangerous form of human skin cancer, suggesting the animals could make an ideal model for studying the disease.
illustrations of cancer cells dividing in pink tones
Cancer Metastasizes Via Fusion of Tumor and Immune Cells: Study
Marcus A. Banks | Jun 17, 2021 | 3 min read
Researchers say evidence of hybridization between leukocytes and cancer indicates that this is a primary means of metastasis. Others disagree.
Opinion: AI Could Aid Cancer Diagnosis, but Caution Is Needed
Adewole S. Adamson | Apr 1, 2021 | 3 min read
While machine learning could improve detection of tumors at their earliest stages, it also risks identifying malignancies that would never cause the patient any harm.
A Multi-omics Approach to Overcome Solid Tumor Drug Resistance
The Scientist | Aug 4, 2020 | 1 min read
Download this research summary to learn about how single-cell proteomics and metabolomics methods unlock drug resistance mechanisms!
George Preti, Organic Chemist Who Studied Human Body Odors, Dies
Amy Schleunes | Mar 20, 2020 | 3 min read
Over nearly 50 years, the Monell Chemical Senses Center chemist investigated a range of topics, from the smell of cancer to body odor’s effects on human physiology and behavior.
Image of the Day: Melanoma Neural Network
Emily Makowski | Dec 9, 2019 | 2 min read
A deep neural network can help determine how likely cancer cells are to metastasize.
custom targeted cancer vaccine
Personalized Cancer Vaccines in Clinical Trials
Jasreet Hundal and Elaine R. Mardis | Jul 15, 2019 | 10+ min read
The field is young, but predicting antigens produced by patients’ malignant cells could yield successful treatments for individuals with a range of cancer types.
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