Targeting Protein Isoforms to Develop Safer Opioids
Targeting Protein Isoforms to Develop Safer Opioids
Inhibiting a protein isoform in the spinal cord alongside morphine improves the opioid’s pain-relieving properties without increasing unwanted side effects.
Inhibiting a protein isoform in the spinal cord alongside morphine improves the opioid’s pain-relieving properties without increasing unwanted side effects.
morphine
Morphine Tolerance Pathway Identified in Mice
David Adam | Sep 20, 2021 | 3 min read
Prolonged exposure to morphine triggers cells in the spine to release signaling molecules that increase pain sensitivity and dull the relief of the drug. Blocking this activity could improve pain management.