Nobel Prize

Gene knockdown using RNAi enables gene function studies, with applications from pest control to biotherapeutics.

David Baker, Demis Hassabis, and John Jumper share this year’s Chemistry award for their research on protein design and structure prediction.

Victor Ambros and Gary Ruvkun won this year’s Physiology or Medicine award for the discovery of microRNA and its role in post-transcriptional gene regulation.

Flies, worms, and fish with rapid development and characterized genetics help scientists uncover fundamental and universal biological processes, and shape cutting-edge research across disciplines.

Carolyn Bertozzi discusses her recent work on targeted degradation therapies that rely on bioorthogonal chemistry.

Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.

Science awards remind us that seemingly overnight success takes years of hard work and patience.

Moungi Bawendi, Louis Brus, and Alexei Ekimov were awarded the Nobel Prize for their work on quantum dots, which has applications in electronics and biomedicine.

Anne L’Huillier, Pierre Agostini, and Ferenc Krausz received this year’s Physics award for creating tools for studying the world of electrons, with future applications in medical diagnostics.

Katalin Karikó and Drew Weissman received this year’s Physiology or Medicine award for their work on RNA biology and mRNA-based vaccines.

From humble yet ingenious beginnings to Nobel recognition, cryogenic electron microscopy (cryo-EM) provides insights into scientific questions that other technologies are unable to answer.

Pathologist Peyton Rous made a groundbreaking discovery in the early 20th century, but his work wasn’t widely recognized until more than 40 years later. 

Seventeen studies coauthored by Gregg Semenza have been retracted, corrected, or raised for concern, and 15 more are currently under investigation.

The award highlights tremendous opportunities for aDNA as well as challenges related to rapid growth, equity, and misinformation.

This year’s award recognizes Carolyn Bertozzi, Morten Meldal, and K. Barry Sharpless for developing click chemistry and bioorthogonal chemistry.

The geneticist’s accomplishments include sequencing Neanderthal DNA and leading the project that identified a new species of hominin, the Denisovans.

The biophysicist shared the 1989 Prize in Chemistry for discovering RNA’s catalytic properties.

Caskey’s contributions to the field were instrumental to modern genetics.

From a Nobel prize and photosynthesis-powered brains to neurodegeneration research and controversy over a new Alzheimer’s drug, a look back at some of the biggest brain-related developments of the year.