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An illustration showing a DNA strand and a cancer cell.
How Some Cancer Cells Survive Chemotherapy
Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells overcome this effect and resist death. 
How Some Cancer Cells Survive Chemotherapy
How Some Cancer Cells Survive Chemotherapy

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells overcome this effect and resist death. 

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells overcome this effect and resist death. 

nucleotides

Collection of pink, green, blue, yellow, and green cubes with A, G, T, C, and a double helix printed on them.
An Overlooked Nucleotide Recycling Pathway Fuels Tumor Growth
Alejandra Manjarrez, PhD | Sep 23, 2024 | 4 min read
When it comes to supplying their purine needs, cancer cells may use salvaged metabolites, according to a study in mice. 
Illustration of a meteorite shower heading for Earth
All RNA and DNA Base Types Are Found in Meteorites, Study Claims
Catherine Offord | Apr 27, 2022 | 2 min read
The discovery could add weight to the hypothesis that the building blocks of life on Earth originally came from space, but some scientists note the possibility of contamination.
Modern Approaches to qPCR
The Scientist | Nov 9, 2020 | 1 min read
Download this ebook to learn how updated qPCR instruments provide optimal thermal performance and data connectivity!
RNA might have incorporated inosine, a derivative of adenosine, in place of guanosine
Primordial RNA May Have Contained Inosine
Catherine Offord | Mar 1, 2019 | 2 min read
The discovery that the adenosine derivative aids self-replication adds weight to the theory that life on Earth originated from a mixture of RNA molecules.
DNA’s Coding Power Doubled
Ruth Williams | Feb 21, 2019 | 3 min read
All life on Earth uses a genetic code based on four nucleotides. Now, scientists have created one with eight.
Novel Method Could Accelerate DNA Synthesis
Sukanya Charuchandra | Jun 19, 2018 | 2 min read
The new technique uses an enzyme found in vertebrate immune systems to attach nucleotides to a growing strand.  
Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine
Catherine Offord | Oct 25, 2017 | 8 min read
With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.
A Different Way of Doing Things
Kivanç Birsoy and David M. Sabatini | Apr 1, 2016 | 10 min read
Cancer cells exhibit altered metabolic processes that may serve as promising targets for new therapies.
Metabolic Reprogramming
Kivanç Birsoy and David M. Sabatini | Mar 31, 2016 | 1 min read
How cancer cells fuel their rapid growth
More Lab-Made Nucleotides
Kerry Grens | Jun 8, 2015 | 2 min read
Artificial bases that act like the real deal can be designed to bind specifically to tumor cells.
Pioneer DNA Researcher Dies
Jef Akst | Oct 2, 2012 | 1 min read
Leonard Lerman, who helped elucidate the process from gene to protein, passed away last month at age 87.
Top 7 in molecular biology
Megan Scudellari | Jun 14, 2011 | 3 min read
A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000.
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