Physiology

Researchers explore the trippy science behind natural hallucinogens in humans. 

Influenza infection activates a pathway that leads to a detrimental drop in progesterone during pregnancy in mice.

Elissavet Chartampila meticulously crafted handwritten labels for her lab tools. Little did she know that some labels last forever.

Jacob Hanna developed a method for replicating embryogenesis outside of the uterus to understand the underlying mechanisms.

Trypanosoma brucei infection induces fat breakdown, but this strategy benefits the host. 

Animals that wind down in the tropics may take us to new frontiers in organ preservation.

Clean and dirty mice respond similarly to allergens, challenging the idea that reduced microbial exposure is the primary cause behind the uptick in allergies.

Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 

Endometrial organoids and single cell analyses helped uncover the molecular mechanisms of a rare uterine condition.

Exercise changes our muscles, but its molecular effects depend on the type of exercise. 

Researchers found new mechanisms and drug targets for cystinosis.

During early pregnancy, the placenta remodels the uterine environment to support fetal growth

Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.

Mice live longer, healthier lives thanks to a gene from their glabrous subterranean cousins.

In this webinar, Benjamin Freedman talks about the importance of organoids in modeling organ function and disease.

After a long soak in the tub, fingers emerge looking like raisins. The real reason for this curious phenomenon lies under the skin.

Diet-derived molecules spur a biological mechanism in the lung barriers of mice that prevents viral lung injury.

In the developing zebrafish, a noisy and asynchronous activity jumpstarts the heart’s journey to coordinated beating.

Learn about the advantages and disadvantages of random integration and targeted approaches for creating transgenic models.