protein structure

Researchers demonstrate that the SARS-CoV-2 spike protein is more stable and binds the human ACE2 receptor with much higher affinity than the spike protein of its closest known relative, bat coronavirus RaTG13.

Folding@Home, currently focused on deciphering the workings of SARS-CoV-2, is the first project to have exascale-level computational muscle.

The UCLA researcher was lauded for figuring out how ATP synthase works.

Metagenomic sequence data boosts the power of protein modeling software to yield hundreds of new protein structure predictions.

See an animation that illustrates emerging insights into the inner ring structures of the nuclear pore complex.

Nature retracts a study six years after an investigation found that the protein structures it reported were fabricated.

Contrary to years of research suggesting otherwise, most aggregated proteins regain their shape and functionality following heat shock.

The gene-editing CRISPR/Cas9 system has three checkpoints to ensure it alters the right section of DNA.

Actin—the bones of the cell—has a preference for swirling into a counterclockwise pattern.

Computational tools take some of the cost—and guesswork—out of drug discovery.

A noncoding RNA initiates translation by grabbing hold of repressor proteins and restricting their functions.

Researchers show that scorpion venom toxins are closely related to defensive proteins from venomous insects.

Robert J. Lefkowitz and Brian K. Kobilka take home this year’s Nobel Prize for Chemistry for revealing how membrane receptors sense and respond to chemical signals.

Irving Geis’s revolutionary painting of sperm whale myoglobin illuminated the nascent field of protein structure.

Check out the latest crop of high-resolution structures and how they inform biological function.

Cyclic peptides, discovered in an African tea used to speed labor and delivery, may hold potential as drug-stabilizing scaffolds, antibiotics, and anticancer drugs.

Assistant Professor, Department of Chemistry and Biochemistry University of California, San Diego. Age: 34