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A cartoon of pills and bacteria along the human intestine.
An Antibiotic That Distinguishes Friend from Foe
A novel compound targets an essential transport system found only in disease-causing bacteria, leaving commensal bacteria unharmed. 
An Antibiotic That Distinguishes Friend from Foe
An Antibiotic That Distinguishes Friend from Foe

A novel compound targets an essential transport system found only in disease-causing bacteria, leaving commensal bacteria unharmed. 

A novel compound targets an essential transport system found only in disease-causing bacteria, leaving commensal bacteria unharmed. 

side effects

a person fumigates a red brick pathway to control mosquitoes in the fight against Dengue virus.
European Medicines Agency Recommends Approving Takeda’s Dengue Vaccine
Katherine Irving | Oct 14, 2022 | 2 min read
In clinical trials, the new inoculation demonstrated greater protection for children and people older than 45 than the existing dengue vaccine.
line of people waiting outside mass vaccination site
“Nocebo” Effect May Cause Majority of COVID-19 Vaccine Symptoms
Natalia Mesa, PhD | Jan 18, 2022 | 2 min read
A negative version of the placebo effect may be behind many instances of mild side effects associated with the jabs, a study suggests.
building sign
Johnson & Johnson Vaccine Garners First Full Approval
Chloe Tenn | Nov 24, 2021 | 1 min read
Health Canada has given the single COVID-19 shot the official greenlight for use in people 18 and older.
a brain surrounded by pills
Years of Prozac Alter Lipids in Young Monkeys’ Brains: Study
James M. Gaines | Sep 10, 2021 | 4 min read
Long-term administration of the antidepressant fluoxetine was tied to decreased concentrations of about 100 different brain lipids in adolescent macaques, hinting at a potential mechanism underlying the drug’s rare but severe side effects.
johnson & johnson johnson&johnson j&j janssen covid-19 vaccine vaccination pandemic adenovirus vector blood clot side effect cerebral venous sinus thrombosis CVST sars-cov-2 coronavirus pandemic astrazeneca
US Health Authorities Ask for Pause in J&J COVID-19 Vaccination
Kerry Grens | Apr 13, 2021 | 2 min read
The FDA and CDC are investigating a handful of reports of blood clots that occurred several days after people received the one-and-done shot.
Blood Clots a Very Rare Side Effect of AstraZeneca Vaccine: EMA
Catherine Offord | Apr 8, 2021 | 2 min read
The European Medicines Agency emphasizes that the benefits of the jab in protecting against COVID-19 still far outweigh the risks.
aripiprazole ability autism spectrum behavior review
Spectrum Reporting Prompts New Review of Common Drug
Jaclyn Jeffrey-Wilensky | Feb 11, 2021 | 3 min read
The review of more than two dozen studies finds aripiprazole has side effects and does not change core autism features, but parents report improvements in self-injury, tantrums, and other challenging behaviors.
WHO Halts Hydroxychloroquine Testing Over Safety Concerns
Catherine Offord | May 27, 2020 | 4 min read
A paper published in The Lancet reported that hospitalized COVID-19 patients taking the drug had a higher risk of death, although some researchers have raised questions about the data.
abilify Aripiprazole autism side effects spectrum
How Aripiprazole’s Promise for Treating Autism Fell Short
Hannah Furfaro | Feb 27, 2020 | 10+ min read
Aripiprazole, marketed as Abilify, is widely thought to be safer than risperidone, the only other drug approved for use in autistic children. A decade’s worth of data suggests that is not true.
Trial of Gene Therapy for Duchenne Muscular Dystrophy Put on Hold
Catherine Offord | Nov 12, 2019 | 2 min read
The US Food and Drug Administration halts a study by Solid Biosciences after a patient experiences severe side effects following treatment.
computing a cure
Artificial Intelligence Shakes Up Drug Discovery
Bianca Nogrady | May 1, 2019 | 8 min read
The pharmaceutical industry is looking to machine learning to overcome complex challenges in drug development.
 immunotherapy  treatment may cause latent infections of Mycobacterium tuberculosis to flare up in cancer patients
Tuberculosis Can Emerge After Cancer Immunotherapy
Ashley Yeager | Apr 1, 2019 | 4 min read
At least a handful of patients have developed active TB after receiving cancer treatment designed to boost the immune system’s antitumor response.
Many Non-Antibiotic Drugs Affect Gut Bacteria
Catherine Offord | Mar 19, 2018 | 2 min read
A new study finds that more than 200 human-targeted, non-antibiotic drugs inhibit the growth of bacterial species that make up part of the human microbiome.
Recipients of Experimental Herpes Vaccine File Lawsuit
Catherine Offord | Mar 14, 2018 | 2 min read
The suit claims that Rational Vaccines, the company of recently deceased researcher William Halford, violated US and international laws when it carried out the procedure.
Opinion: Token Pharmacovigilance
Peter Doshi | May 23, 2017 | 3 min read
A US government website for collecting reports of side effects associated with vaccines is broken. Why has no one noticed?
Circadian Atlas Chronicles Gene Expression
Kate Yandell | Oct 27, 2014 | 3 min read
Researchers have mapped the times of day when mouse genes are transcribed across 12 organs.
Gene a Pain for Statin Users
Kate Yandell | Aug 28, 2013 | 3 min read
A genetic variant may help explain why some patients experience muscle discomfort and dysfunction while taking the cholesterol-lowering medications.
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