aging

David Furman uses computational power, collaborations, and cosmic inspiration to tease apart the role of the immune system in aging.

Agnès Lacreuse investigates cognitive aging and women’s health in nonhuman primates.

Citizen scientists help monitor monkey immune cells, providing a foundation for future work on stress, sociality, and aging.

Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight.

Murine T cells that survived at least four host lifetimes offer insights into immunological senescence. 

Increasing levels of the protein Trio preserved synaptic function and motor abilities in aging flies.

Yejing Ge explores the behavior of skin-resident stem cells in wound repair, cancer, and aging.

After sequencing centromeres in humans and other primates, researchers found that they vary greatly across species and potentially contribute to aging and disease.

Biochemist Sharon Stack hopes to advance the field of ovarian cancer by exploring the tumor and host-related factors that influence its metastatic process. 

Removing excess iron from aging mouse blood-forming cells enhances their regenerative capacity.

In rats, motherhood leaves long-term biological signatures in a brain region that is crucial for learning and memory.

Neurons linked to metabolic processes slow aging in mice.

Not all degenerated intervertebral discs are painful; a new study identified a subset of disc cells that triggers a pathway to pain.

Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 

The relationship between aging and cancer is complex, with several shared underlying mechanisms. 

Data from a highly resilient individual guided researchers to new potential therapeutic targets.

A new mouse model shows that the Myc protein has complex effects on aging and cancer.

Hair-coloring stem cells must swing back and forth between their maturity states to give hair its color.

How will a new version of epigenetic clocks aimed at validating the age of people older than 100 years of age balance accuracy and anonymity?