ADVERTISEMENT
3D ribbon structure of protein domains studied in proteomics research
The Power of Proteomics
Proteomic analysis provides scientists with a deeper understanding of the molecular events that influence health and disease.
The Power of Proteomics
The Power of Proteomics

Proteomic analysis provides scientists with a deeper understanding of the molecular events that influence health and disease.

Proteomic analysis provides scientists with a deeper understanding of the molecular events that influence health and disease.

aging

Digitized outline of a person surrounded by binary inputs with a DNA strand running down the center of the image.
Pioneering the Aging Frontier with AI Models
Shelby Bradford, PhD | Dec 13, 2024 | 8 min read
David Furman uses computational power, collaborations, and cosmic inspiration to tease apart the role of the immune system in aging.
Image of two marmosets perched on a branch.
From Marmosets to Menopause: A Primate Perspective
Laura Tran, PhD | Nov 1, 2024 | 2 min read
Agnès Lacreuse investigates cognitive aging and women’s health in nonhuman primates.
A baby rhesus macaque against a forest backdrop.
White Blood Cells, Hurricanes, and the Monkeys of Cayo Santiago
Hannah Thomasy, PhD | Oct 1, 2024 | 2 min read
Citizen scientists help monitor monkey immune cells, providing a foundation for future work on stress, sociality, and aging.
An illustration of a purple and blueribosome using mRNA as a template to synthesize a red protein chain.
A Small RNA with a Big Impact on Cell Aging
Kamal Nahas, PhD | Oct 1, 2024 | 4 min read
Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight.
A dark blue T cell with light blue and yellow structures on its surface.
Epigenetic Clocks Continue to Tick Over Multiple Lifetimes
Hannah Thomasy, PhD | Sep 17, 2024 | 5 min read
Murine T cells that survived at least four host lifetimes offer insights into immunological senescence. 
Six tubes, each with black dots representing flies, each fly encircled in blue, green, or red.
Combating Age-Related Motor Decline
Aparna Nathan, PhD | Aug 23, 2024 | 4 min read
Increasing levels of the protein Trio preserved synaptic function and motor abilities in aging flies.
Three images of a hand with an abrasion progressing from most recently injured (left) to most healed (right).
Stem Cell Plasticity: A Double-Edged Sword
Hannah Thomasy, PhD | Jun 14, 2024 | 5 min read
Yejing Ge explores the behavior of skin-resident stem cells in wound repair, cancer, and aging.
Several X-shaped duplicated chromosomes floating on a blurry blue background.
Centromeres Mutate More Rapidly Than Expected
Kamal Nahas, PhD | May 30, 2024 | 4 min read
After sequencing centromeres in humans and other primates, researchers found that they vary greatly across species and potentially contribute to aging and disease.
An artistic illustration of the female reproductive system.
Outsmarting Ovarian Cancer
Mariella Bodemeier Loayza Careaga, PhD | May 8, 2024 | 4 min read
Biochemist Sharon Stack hopes to advance the field of ovarian cancer by exploring the tumor and host-related factors that influence its metastatic process. 
Red and gray round cells floating on a red background. 
Low Intracellular Iron Levels May Keep Blood Stem Cells Young
Alejandra Manjarrez, PhD | Apr 8, 2024 | 3 min read
Removing excess iron from aging mouse blood-forming cells enhances their regenerative capacity.
A white and tan mother rat watches over several rat pups. 
Babies on the Brain
Hannah Thomasy, PhD | Apr 1, 2024 | 2 min read
In rats, motherhood leaves long-term biological signatures in a brain region that is crucial for learning and memory.
Illustration of a web of dark blue neurons with a purple glow at the center of each neuron.
How the Brain Hits the Brakes on Aging 
Aparna Nathan, PhD | Mar 18, 2024 | 4 min read
Neurons linked to metabolic processes slow aging in mice.
Back Pain Explained
Rachael Moeller Gorman | Feb 5, 2024 | 4 min read
Not all degenerated intervertebral discs are painful; a new study identified a subset of disc cells that triggers a pathway to pain.
A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
Aging and Cancer
Aging and Cancer
Rebecca Roberts, PhD | Nov 14, 2023 | 6 min read
The relationship between aging and cancer is complex, with several shared underlying mechanisms. 
Cropped view of senior man playing with puzzles
A Rare Genetic Mutation Protects Against Alzheimer's Disease
Hannah Thomasy, PhD, Drug Discovery News | Sep 17, 2023 | 4 min read
Data from a highly resilient individual guided researchers to new potential therapeutic targets.
Close up on eyes of mother and daughter faces next to one another
A Long and Unhealthy Life?
Aparna Nathan, PhD | Sep 13, 2023 | 3 min read
A new mouse model shows that the Myc protein has complex effects on aging and cancer.
Melanocyte stem cells are shown in red and other cell nuclei are shown in blue.
Hair Turns Gray Due to Stuck Stem Cells
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 3 min read
Hair-coloring stem cells must swing back and forth between their maturity states to give hair its color.
An elderly person in beige shirt and a knitted, cream-colored vest holds a wooden walking stick.
New Epigenetic Clocks May Confirm Extreme Age
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
How will a new version of epigenetic clocks aimed at validating the age of people older than 100 years of age balance accuracy and anonymity?
ADVERTISEMENT