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An illustration of an orange tau fibril in front of a blue background.
Uncovering the Unexpected: Developing a Novel Anti-Tau Therapy
Ke Hou generated a compound that prevents tau aggregation in the murine brain, but the potential Alzheimer’s disease therapy also had a surprising property.
Uncovering the Unexpected: Developing a Novel Anti-Tau Therapy
Uncovering the Unexpected: Developing a Novel Anti-Tau Therapy

Ke Hou generated a compound that prevents tau aggregation in the murine brain, but the potential Alzheimer’s disease therapy also had a surprising property.

Ke Hou generated a compound that prevents tau aggregation in the murine brain, but the potential Alzheimer’s disease therapy also had a surprising property.

Drug Discovery & Development

Gram-negative, rod-shaped bacteria expressing pili.
Building Bacterial Drug Factories
Aparna Nathan, PhD | Dec 30, 2024 | 3 min read
Drug-manufacturing bacteria can provide a more targeted approach to treat gut diseases.
A man holds his knee and grimaces in pain while sitting in front of a bridge.
A Nanoparticle Approach to Treat Torn Tendons
Aparna Nathan, PhD | Dec 29, 2024 | 4 min read
Alayna Loiselle has found a way to bring therapeutics straight to an injured tendon.
Graphic depicting a tumor being targeted by a drug
Great Anticancer Potential Comes in a Small Package 
Niki Spahich, PhD | Dec 28, 2024 | 4 min read
Jingjing Sun developed a novel, ultra-small nanocarrier that actively targets tumor cells.
A conceptual illustration of scientists evaluating potential kinase inhibitors.
Leveraging Recombinant Kinases for Drug Discovery Research
The Scientist and Sino Biological | Dec 26, 2024 | 3 min read
As kinase dysfunction underlies many pathological conditions, scientists require high-quality active kinases for their therapeutic development programs.
3D conceptual image of antibodies on a blue background.
Improving the Efficiency and Reliability of Fully Human Antibody Drug Development
The Scientist Staff | Dec 16, 2024 | 2 min read
Microfluidic technology enables high-throughput, droplet-based antibody discovery in fully human antibody mice.
Brightfield microscopy image of Aspergillus fumigatus.
The Silent Pandemic of Antifungal Resistance
Danielle Gerhard, PhD | Dec 16, 2024 | 2 min read
As the world grapples with antimicrobial-resistant bacteria, another insidious threat looms large: drug-resistant fungi.
New Frontiers in Vaccine Development
New Frontiers in Vaccine Development
The Scientist Staff | Dec 12, 2024 | 2 min read
Discover how scientists are designing the next groundbreaking vaccines against infectious diseases.
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Evotec SE announces first projects for LAB eN² drug discovery accelerator with Novo Nordisk
Evotec | Dec 11, 2024 | 3 min read
Novo Nordisk and Evotec select three projects from Boston University, Harvard University in collaboration with Mass General Brigham, and Joslin Diabetes Center to be developed within LAB eN² focusing on cardiometabolic diseases
Beckman logo
Beckman Coulter Life Sciences Accelerates Drug Discovery with Launch of Cydem VT Automated Clone Screening System
Beckman Coulter Life Sciences | Dec 4, 2024 | 2 min read
High-Throughput Platform Reduces Manual Steps by up to 90%
Scientist at lab bench holding a pipette with a microscope and glassware in the foreground.
Improving Drug Analysis with Supercritical Fluid Chromatography
Shimadzu | Dec 2, 2024 | 1 min read
Researchers easily separate chiral and achiral compounds for drug analysis and purification.
A photo of a 96-well microplate showcasing serial dilutions of purple dye solution.
Achieving Consistency in Serial Dilutions
The Scientist Staff | Dec 2, 2024 | 2 min read
Researchers ensure the success of their serial dilution-based assays by using optimized protocols and advanced liquid handling tools.
An illustration of mRNA molecules.
Probing the Structure of mRNA Molecules
Shimadzu | Nov 25, 2024 | 1 min read
Learn how scientists examine mRNA quality using an easy-to-operate LC-MS system.
Drugging the Undruggable
Drugging the Undruggable
The Scientist Staff | Nov 19, 2024 | 1 min read
Learn how cutting-edge strategies empower researchers to target undruggable proteins.
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Takara Bio launches high-throughput, cost-effective qPCR system to advance clinical research
Takara Bio | Nov 19, 2024 | 2 min read
The SmartChip ND system meets laboratories’ needs for flexibility, scalability, efficiency, and affordability.
A cartoon of pills and bacteria along the human intestine.
An Antibiotic That Distinguishes Friend from Foe
Sneha Khedkar | Nov 19, 2024 | 4 min read
A novel compound targets an essential transport system found only in disease-causing bacteria, leaving commensal bacteria unharmed. 
Nathalie Fuentes, a senior scientist at AstraZeneca, is shown completing two of her roles: on the left, she prepares regulatory paperwork for a new drug, while on the right, she documents information from stability testing a new drug.
The Secrets of Securing a Senior Scientist Role in an Industry
Shelby Bradford, PhD | Nov 15, 2024 | 5 min read
Nathalie Fuentes shared her experience of landing a unicorn position in a pharmaceutical company after a postdoctoral fellowship.
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CN Bio launches PhysioMimix Bioavailability assay kit: Human 18
CN Bio | Nov 14, 2024 | 3 min read
Harnessing the capabilities of the PhysioMimix Multi-organ System, the kit enhances lead optimization and preclinical testing pipelines, providing an all-in-one solution to generate predictive insights into human oral bioavailability, and better inform lead candidate selection.
Sapio Sciences
Sapio Sciences Expands Collaboration With AWS to Advance Science-Aware AI Vision
Sapio Sciences | Nov 8, 2024 | 2 min read
Collaboration enables customers to securely and confidently use AI to accelerate drug research and discovery.
An illustration of purple proteins on a dark background.
Exploring the Proteome in Search of New Biomarkers
SomaLogic | Nov 7, 2024 | 1 min read
Discover how a precise, high-throughput proteomics assay enables researchers to uncover previously unidentified biomarkers.
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