Cell & Molecular Biology

Acting as mini organs in a dish, organoids fuel diverse research areas, from cancer to evolutionary biology.

How does exercise benefit health? Molecules called exerkines partly regulate its effects and provide therapeutic targets to mimic the benefits of exercise. 

Venoms from four different snake species work differently to disrupt blood vessels.

Giovanna Prout from Scale Biosciences discusses the inspiration for and results of the company’s ambitious single-cell sequencing endeavor.    

Investigating how reindeers shed and regenerate their antlers offers clues into mammalian organ regeneration.

The TREM2 receptor may hold the keys to understanding how myeloid cells affect immune responses to neurological disorders and cancer.

Anne Madden sees the beauty and brawn of creepy-crawly microbes and how they may hold the solution to many human problems.

Gene expression of lactose-digesting genes is controlled by the lac operon that accounts for varying amounts of lactose or glucose in the cell.

David Furman uses computational power, collaborations, and cosmic inspiration to tease apart the role of the immune system in aging.

In a century, Wolbachia has gone from a master reproductive manipulator to a partner in the fight against pathogens, exemplifying how a microbe can shape hosts and diseases.

The discovery of an inducible switch in Escherichia coli that controlled lactose metabolism offered the first clues into gene expression.

Researchers tweak heart-forming organoids to produce blood cells, in a process that mimics embryonic development.

Novel assay offers a highly sensitive and specific method to detect recombinant proteins containing the human IgG Fc domain.

Explore proteomics concepts, approaches, and data analysis.

Application Note No. 490 “Reliable Protection Against Pipetting-Related Bio-Aerosol Contamination with ep Dualfilter T.I.P.S. Pipette Tips” describes the generation of aerosols when working with biological samples and the resulting contamination risk during pipetting. 

Multi-tissue dissociation kits provide a versatile and robust solution for streamlining single-cell dissociation workflows.   

Human brain and blood vessel organoids merged to form blood-brain barrier assembloids could provide clues into neurological diseases.

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. 

Researchers ensure the success of their serial dilution-based assays by using optimized protocols and advanced liquid handling tools.