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Watercolor illustration of DNA helix overlaid on colorful background with different medications.
Circumventing Cancer Resistance
Bishoy Faltas investigates how chemotherapy, extrachromosomal DNA, and a gene-editing protein create the perfect storm for bladder cancer therapeutic resistance.
Circumventing Cancer Resistance
Circumventing Cancer Resistance

Bishoy Faltas investigates how chemotherapy, extrachromosomal DNA, and a gene-editing protein create the perfect storm for bladder cancer therapeutic resistance.

Bishoy Faltas investigates how chemotherapy, extrachromosomal DNA, and a gene-editing protein create the perfect storm for bladder cancer therapeutic resistance.

Genetics

Two female scientists in lab coats and safety glasses are studying epigenetics. One uses a dropper to add a chemical to a test tube held by the other. In the background are a DNA double helix, histones and chromatin structure, and environmental factors that affect the epigenome.
Epigenetics and Heritable Control of Gene Expression
Rebecca Roberts, PhD | Dec 18, 2024 | 7 min read
The epigenome regulates nearly every process in the human body. By studying epigenetics, scientists have revealed some secrets to aging, cancer, and complex diseases.
Newborn heel prick test for genetic screening
Transforming Molecular Workflows for Newborn Screening 
The Scientist and Revvity | Dec 17, 2024 | 3 min read
New PCR-based approaches simplify molecular testing for health issues in infants, making diagnostic approaches simpler and more accessible across laboratories.
An illustration showing a tumor in a human colon.
Colorectal Tumors are Born When Stem Cells Die
Sahana Sitaraman, PhD | Dec 16, 2024 | 5 min read
New research describes the early steps of colorectal tumor formation and lays a foundation for improving diagnosis and treatment of aggressive cancers.
Illustration of a blue piece of DNA with a red segment in its middle on a purple background. Blue and red segments that have been cut out surround the larger strand.
Splicing Fungal Genes Help Cells Change Shape
Shelby Bradford, PhD | Dec 16, 2024 | 2 min read
Candida albicans uses alternative splicing to morph into a filamentous form during fevers.
Image of colored blobs comprised of individual dots. Each dot represents an immune cell and dots of the same color belong to the same cell type.
Charting the Human Immune Health Atlas
Laura Tran, PhD | Dec 16, 2024 | 2 min read
Researchers mapped the landscape of healthy immune cells from childhood through adulthood.
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The Regulation of the lac Operon
Shelby Bradford, PhD | Dec 13, 2024 | 4 min read
Gene expression of lactose-digesting genes is controlled by the lac operon that accounts for varying amounts of lactose or glucose in the cell.
3D illustration of RNA polymerase (blue, middle) transcribing a segment of DNA (purple) into an RNA chain (red, extending to top).
The lac Operon: A Lesson in Simple Gene Regulation
Shelby Bradford, PhD | Dec 13, 2024 | 10+ min read
The discovery of an inducible switch in Escherichia coli that controlled lactose metabolism offered the first clues into gene expression.
Image of Brussels sprouts and endives on a wooden background.
Greens and Genes: The Bitter Truth Behind Your Veggie Preferences
Laura Tran, PhD | Dec 10, 2024 | 5 min read
From Brussels sprouts to chicory, some veggies pack a bitter punch, but genetics and individual differences create a unique flavor experience for everyone.
Image of a mangrove forest and river in Thailand.
Tackling Mangrove Protection Challenges in Thailand
The Scientist and MGI Tech | Dec 5, 2024 | 9 min read
High-throughput sequencing technology supports mangrove protection efforts.
A woman eating a piece of multigrain bread.
How did Humans Adapt to Digest Starchy Foods?
Hannah Thomasy, PhD | Dec 5, 2024 | 4 min read
Researchers uncover the surprisingly complex evolutionary history of the salivary protein amylase.
The image shows an individual sea anemone of the species Nematostella vectensi against a black background. 
Elusive Stem Cell Population Finally Identified in Sea Anemones
Claudia Lopez-Lloreda, PhD | Dec 5, 2024 | 4 min read
The presence of a previously unidentified population of stem cells in sea anemones suggests that these cells may have been present in a common cnidarian ancestor.
New Approaches for Decoding Cancer at the Single-Cell Level
New Approaches for Decoding Cancer at the Single-Cell Level
The Scientist Staff | Dec 2, 2024 | 1 min read
In this webinar, Linghua Wang and Jeremy Goecks will talk about technology that enables new approaches for a better understanding of tumors on a cellular, spatial, and environmental level.
Discover How Single-Cell Sequencing Can Clarify Tumor Complexity
Molecular-Level Dissection of the Tumor Microenvironment 
10x Genomics | Dec 2, 2024 | 1 min read
An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. 
A brittle star with its thin, serpent-like arms against a black background.
Diving Into the Brittle Star Genome to Understand the Evolution of Regeneration
Sneha Khedkar | Nov 22, 2024 | 4 min read
The sequenced genome of the brittle star revealed unique gene arrangements and provides insights into ancient genes involved in limb regeneration.
A pink and yellow protein held together by a gray circle pull a piece of blue DNA into a loop.
Combining Bacterial Systems Offers a New Approach to Gene Regulation
Shelby Bradford, PhD | Nov 22, 2024 | 4 min read
Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression.
DNA sequencing illustration
Benchtop Instruments Bring About a Modern Age of NGS
The Scientist Staff | Nov 18, 2024 | 4 min read
Emmanuel Naouri from Illumina discusses recent innovations that promise to support new and established next-generation sequencing (NGS) users.
Conceptual image of DNA sequencing map with concentric multicolor squares on a white background.
Streamlining NGS Sample Preparation with Automation 
The Scientist Staff | Nov 15, 2024 | 2 min read
Cutting-edge microfluidics enables full automation of NGS protocols.
Illustration of four speakers on a panel facing an audience with a blue background behind them.
Spotlighting the Science in Sci-Fi
Shelby Bradford, PhD | Nov 15, 2024 | 2 min read
Carlo Quintanilla talks about the real science behind science fiction at popular culture conventions.
Chickens on a farm.
A Wastewater Surveillance Program Sounds the Alarm on Avian Influenza
Deanna MacNeil, PhD | Nov 14, 2024 | 6 min read
Born from the COVID-19 pandemic, a viral-agnostic approach blends sequencing research and public health to get ahead of bird flu transmission.
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