Cancer development and progression is driven by transcriptional, cellular, and spatial changes. Identifying and understanding these changes is essential to better characterizing tumor pathology and developing potential therapeutics. Single-cell sequencing lets researchers screen the various different cell types in a tumor, and new technologies add spatial information to the mix, letting scientists accurately delineate the healthy and cancer cell populations within complex tumor tissues.
Download this application note from 10x Genomics to learn how scientists used a 380-gene immuno-oncology panel to study tumor organization and the tumor microenvironment in ovary, lung, pancreatic, and brain cancer samples.