Biochemistry

As kinase dysfunction underlies many pathological conditions, scientists require high-quality active kinases for their therapeutic development programs.

Long seen as collective contaminants, some bacterial species actually promote bioethanol production.

The liver breaks down dietary fructose into lipids that are used by cancer cells to boost their growth in mice.

Gene expression of lactose-digesting genes is controlled by the lac operon that accounts for varying amounts of lactose or glucose in the cell.

Researchers mimic the antianxiety effects of psychedelics by identifying and activating specific brain regions in an important step towards developing therapeutics that do not cause hallucinations.

Researchers tweak heart-forming organoids to produce blood cells, in a process that mimics embryonic development.

Explore proteomics concepts, approaches, and data analysis.

Ticks form a stable structure around their mouth to stick to their hosts for days. Phase transitions of proteins in the tick saliva drive this adhesion.

Multi-tissue dissociation kits provide a versatile and robust solution for streamlining single-cell dissociation workflows.   

Researchers easily separate chiral and achiral compounds for drug analysis and purification.

A bacterium found in the wound microbiome can accelerate healing, highlighting the potential for microbiota-based wound therapies.

With a plug-and-play strategy, researchers engineer proteins with new functions.

In mice, a ketogenic diet remodeled the translatome of pancreatic cancer cells, rendering them vulnerable to targeted therapy.

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells overcome this effect and resist death. 

Learn how scientists examine mRNA quality using an easy-to-operate LC-MS system.

Pseudomonas infections are tough to treat, but a new study reveals a chemical they use to subdue macrophages, suggesting new therapeutic avenues.

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression.

An enzyme synthesized in the fly gut travels to the brain, where it induces insulin-like peptide secretion.

Cutting-edge microfluidics enables full automation of NGS protocols.