Alzheimer's Disease

The TREM2 receptor may hold the keys to understanding how myeloid cells affect immune responses to neurological disorders and cancer.

Researchers used artificial intelligence in large genomics studies to fill in gaps in patient information and improve predictions, but new research uncovers false positives and misleading correlations.

Cellular oxygen consumption in the brain may shed new light on Alzheimer’s disease onset, progression, and treatment.

Popular weight-loss drugs like Ozempic are used to treat obesity and diabetes. Now, researchers found that these drugs also affect rodent brains in other ways. 

Researchers investigate tauopathy mechanisms and turn to tau detection methods to help improve health care outcomes and lower the economic burden of these diseases.

Durable analytical instruments expedite the study of misfolded proteins linked to neurodegenerative diseases.

Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.

In this webinar, Douglas Marchuk and Viviana Gradinaru will discuss how scientists can overcome physiological barriers preventing gene therapies from reaching the brain. 

Brain region-specific spheroids help scientists find new compounds to treat opioid use disorder and more.

Scientists discuss their latest findings on cell secretory states, synapse formation, and neurodegenerative disease.

Intermittent fasting regulates biological time and improves disrupted sleep in an Alzheimer’s disease model.

Data from a highly resilient individual guided researchers to new potential therapeutic targets.

Mutations that accumulate as one ages contribute to various neurological disorders.

Understanding the role of immune cells in neurodegeneration may help scientists develop new diagnostic, prognostic, and treatment tools.

Dialing up the activity of a protein called SYK in the brain’s “janitors” could provide an avenue to treat Alzheimer’s and other neurodegenerative diseases.

The APOE4 variant causes cholesterol buildup in the cells that make protective fatty sheaths for neurons, possibly helping explain its role in neurodegeneration.

An influential paper on amyloid protein and Alzheimer’s disease potentially fabricated data. Why did it take 16 years to flag?

Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.

Researchers use Single Molecule Counting (SMC®) technology to probe brain biomarkers.