Cancer

When it comes to supplying their purine needs, cancer cells may use salvaged metabolites, according to a study in mice. 

Administering immunotherapy when the tumor microenvironment is most susceptible to T cells enhances treatment efficacy in mice.

Sequencing advances deliver comprehensive insights into how genomic variation drives cancer initiation and progression.

Murine T cells that survived at least four host lifetimes offer insights into immunological senescence. 

Using a library preparation kit optimized for cell free DNA (cfDNA) provides high quality data for early cancer detection.

Instead of an on-off toggle switch, cancer cells adapt through a series of distinct states of increasing drug resistance.

Scientists have identified a new variant of the cell cycle that could provide insight into how diseases like cancer occur. 

Samples are commonly stored in a way that degrades RNA. Scientists are devising new ways to overcome this obstacle for RNA sequencing. 

In this webinar, Edward Han, Jospeh Zenga, and Tyce Kearl will discuss how optofluidic technologies unlock key immuno-oncology insights for translational applications.

This single test interrogates over 500 genes to profile a patient’s solid tumor, helping to increase the likelihood of identifying an immuno-oncology biomarker or clinically actionable biomarkers that enable targeted therapy options or clinical trial enrollment.

Green algae can be outfitted with nanoparticles, transforming them into efficient drug-delivering machines that target lung tumors.

From normal vertebrate development to tumor cell cannibalism, cell-in-cell events occur in many different contexts across the tree of life.

The emergence of innovative analytical methods empowers researchers to comprehensively characterize tumor samples.

A protein in natural killer cells keeps them from turning into more docile counterparts.

Assay Automation Makes Cutting-Edge Research More Accessible to Labs

Irene Ghobrial sequences circulating tumor cells in blood samples to genomically profile patients with multiple myeloma.

Industry expertise helps scientists navigate and streamline antibody-drug conjugate research and development.

Researchers explore the immune system to further understand cancer and illuminate therapy development.

A nutrient-based nanomedicine stopped runaway tumor growth in mice by firing up a latent metabolic pathway.