cell & molecular biology

Researchers need to start with a reliable process for commercial biopharmaceutical production in living cells.

A new method for isolating extracellular fluid aims to discover molecules with therapeutic potential that were previously obscured by highly abundant proteins.

A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.

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The approach could help test hypotheses about how atypical function of the brain’s immune cells contributes to autism.

Viscous solutions accelerate the migration of tumor cells and may enable metastasis, according to a new study.

The tiny strings of RNA promote translation of a protein implicated in cancer, a hint they could regulate gene expression in more ways than previously thought.

His work blended biology and the methods of theoretical physics to explain neural networks. 

Tiny hairlike structures on pancreatic cells have long been considered static sensors. Now, researchers say they move and help regulate insulin secretion.

Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.

Stressed cells can form hollow actin bridges to neighbors to get help, but the virus may hijack these tiny tunnels for its own purposes, a study suggests.

At about 2 centimeters in length, Thiomargarita magnifica tests scientists’ notions of how large microbes can grow.

3-D cell culture narrows the gap between in vitro and in vivo.

Learn more about cell culture best practices.

Researchers explore the idea that molecular patterns in individual cells could underlie the development of a left and a right in animals.

Researchers use imaging to show how actin fibers tilt and then swirl to create left-right asymmetry in the cell.

An RNA-modifying enzyme passed to daughter cells during budding allows yeast cells to switch between faster- and slower-growing phenotypes.

As the year draws to a close, we look back on researchers we bid farewell to, and the contributions they made to their respective fields.

Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.