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Gram-negative, rod-shaped bacteria expressing pili.
Building Bacterial Drug Factories
Drug-manufacturing bacteria can provide a more targeted approach to treat gut diseases.
Building Bacterial Drug Factories
Building Bacterial Drug Factories

Drug-manufacturing bacteria can provide a more targeted approach to treat gut diseases.

Drug-manufacturing bacteria can provide a more targeted approach to treat gut diseases.

drug delivery

A man holds his knee and grimaces in pain while sitting in front of a bridge.
A Nanoparticle Approach to Treat Torn Tendons
Aparna Nathan, PhD | Dec 29, 2024 | 4 min read
Alayna Loiselle has found a way to bring therapeutics straight to an injured tendon.
Drugging the Undruggable
Drugging the Undruggable
The Scientist Staff | Nov 19, 2024 | 1 min read
Learn how cutting-edge strategies empower researchers to target undruggable proteins.
Learn How Researchers Advance Targeted Drug Development
Stay on Target: Overcoming Challenges in Precision Drug Delivery
The Scientist and Taconic | Oct 24, 2024 | 1 min read
Explore how on-target precision therapies improve patient outcomes and drug tolerability.
A cat head and human head are seen in profile against a blue background, white and purple Toxoplasma parasites pass between them.
Genetically Engineered Parasites Smuggle Therapeutics into the Brain
Hannah Thomasy, PhD | Oct 23, 2024 | 4 min read
Scientists modified Toxoplasma gondii to deliver a potential Rett Syndrome therapeutic to the mouse brain. 
Pseudo-colored scanning electron microscope image of the algae microrobot with the algae in green and the drug-filled nanoparticles in orange.
Green Warriors: Algae Microrobots Set to Combat Metastasis
Laura Tran, PhD | Aug 26, 2024 | 4 min read
Green algae can be outfitted with nanoparticles, transforming them into efficient drug-delivering machines that target lung tumors.
From the Expert: Click Chemistry and Bioorthogonal Applications
From the Expert: Click Chemistry and Bioorthogonal Applications
The Scientist | Feb 13, 2024 | 1 min read
Carolyn Bertozzi discusses her recent work on targeted degradation therapies that rely on bioorthogonal chemistry.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
How Vesselon Can Improve the Entire Class of Radiopharmaceuticals
Clayton Larsen - President & CEO, Vesselon, Inc. | Nov 21, 2023 | 3 min read
Vesselon's microspheres optimize radiopharmaceuticals for targeted treatment, enhancing anti-tumor effects.
How Vesselon Can Improve the Entire Class of Antibody-Drug Conjugates
Clayton Larsen - President & CEO, Vesselon, Inc. | Oct 30, 2023 | 4 min read
Vesselon’s novel co-formulation of gas lipid microspheres and self-assembling liposomes, targeted and activated by commercial ultrasound, would be an ideal adjunct to any of these ADC drugs.
Image shows photorhabdus virulence cassettes (green) binding to insect cells (blue) prior to injection of payload proteins. 
Engineered Bacterial “Syringes” Can Deliver Drugs Into Human Cells
Rohini Subrahmanyam, PhD | Apr 20, 2023 | 4 min read
Researchers repurpose tiny bacterial injection systems to specifically inject a wide variety of proteins into human cells and living mice.
Optimize Exosome Isolation with Ultracentrifugation
Capturing Exosomes from Cell Culture Media
Thermo Fisher Scientific | Mar 13, 2023 | 1 min read
Scientists choose ultracentrifugation techniques for simplicity and proven efficacy in exosome purification.
Structure of a Chlamydomonas, green algae
Drugs Hitch a Ride on Algae for Targeted Delivery
Holly Barker, PhD | Feb 1, 2023 | 3 min read
A new microrobot uses algae to transport antibiotics into the lungs of mice with pneumonia.
Illustration showing microscopic algae swim through mouse lungs and deliver nanoparticles of an antibiotic attached to their surfaces
Infographic: Algae Robots Transport Antibiotics to Infected Tissues
Holly Barker, PhD | Feb 1, 2023 | 1 min read
Microscopic algae dotted with drug-filled nanoparticles may offer a more effective means of treatment than traditional delivery methods.
 Discover the Latest in Using Nanoparticles for Therapeutic Applications 
Using Nanoparticles in Targeted Drug Delivery and Photothermal Therapy
nanoComposix | Nov 18, 2022 | 1 min read
Discover the latest research and advances in nanoparticle technology. 
Lipid nanoparticle delivers treatment to a cancer cell.
Researchers Develop a CRISPR-Based Therapy That Penetrates Solid Tumors
Jennifer Zieba, PhD | Oct 10, 2022 | 3 min read
By packaging lipid nanoparticles with elements that decrease the fibrous nature of solid tumors, researchers can deliver CRISPR therapies in a more efficient manner.
Learn How Scientific Innovation Creates Industry Opportunities
Understanding Biopharma Market Trends and the Innovations That Drive Them
Tecan | Sep 26, 2022 | 1 min read
Explore the latest science shaping the healthcare sector.
A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
Alejandra Manjarrez, PhD | Sep 23, 2022 | 5 min read
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.
Building a Synthetic Biology Platform for Drug Delivery
Building a Synthetic Biology Platform for Drug Delivery
The Scientist | Aug 4, 2022 | 1 min read
Kate Adamala and Niren Murthy will discuss the latest advances in drug delivery using synthetic biology approaches.
Linking Biological Clocks and Cancer Therapeutics to Minimize Toxicity
It’s All in the Timing: Optimizing Chemotherapy Administration
Sejal Davla, PhD | Mar 1, 2022 | 1 min read
How the biological clock influences chemotherapy success
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