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A person sitting in a gym with a protein shake bottle and kettlebell placed beside them.
Exerkines: Molecular Messengers That Mediate Exercise Effects 
How does exercise benefit health? Molecules called exerkines partly regulate its effects and provide therapeutic targets to mimic the benefits of exercise. 
Exerkines: Molecular Messengers That Mediate Exercise Effects 
Exerkines: Molecular Messengers That Mediate Exercise Effects 

How does exercise benefit health? Molecules called exerkines partly regulate its effects and provide therapeutic targets to mimic the benefits of exercise. 

How does exercise benefit health? Molecules called exerkines partly regulate its effects and provide therapeutic targets to mimic the benefits of exercise. 

metabolites

3D illustration of dark, oval parasites invading translucent host cells with blue nuclei.
Live Imaging Intracellular Parasites Reveals Changes to Host Metabolism
Shelby Bradford, PhD | Nov 6, 2024 | 4 min read
Researchers found that Toxoplasma gondii increased the host cell’s metabolic activity, offering insights into potential treatment strategies.
MRI scan of a human head in profile
Gut Microbe Metabolites Lower Levels of Toxic Tau
Kamal Nahas, PhD | Jul 9, 2024 | 5 min read
Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.
Photo of a line of grassy plants with the roots under the soil visible.
Plants Defend Themselves Against Heavy Metals
Shelby Bradford, PhD | Jun 13, 2024 | 3 min read
A metabolite from maize roots protects the plants against arsenic toxicity.
A block of cheddar cheese pictured here with various accompaniments. 
Cheddar Cheese Lovers Have Interactive Microbes to Thank
Vaishnavi Sridhar, PhD | May 16, 2024 | 3 min read
Scientists used a commercial year-long cheddar making process to show how various bacterial communities interact and contribute to the distinct flavor of cheddar.
Abstract drawing of microbes.
Exploring Microbial Dark Matter
Kamal Nahas, PhD | Apr 19, 2024 | 4 min read
An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds. 
Fatty Feasts May Come at an Immune Cost
Shelby Bradford, PhD | Jan 25, 2024 | 4 min read
Dietary changes rapidly alter T cell metabolism, but the effects can be reversed.
Cheese wheels with moldy rinds on a wooden plank
Deleting a Gene Quells a Pesky Cheese-Destroying Fungus
Natalia Mesa, PhD | Jun 30, 2023 | 3 min read
Fungi disrupt microbial communities on cheese by making antibiotics. 
Droplet of DNA lysate
Optimizing Sample Homogenization
The Scientist and Bertin Technologies | May 23, 2023 | 3 min read
Discover how the latest homogenization technology improves and simplifies the processing of any biological sample.
a mouse moves away from the camera, its left leg caught in a cloth
Scientists Discover New “Superfast” Muscle Fibers in Mouse Limbs
Katherine Irving | Feb 9, 2023 | 4 min read
Fast twitch fibers like these could one day be used to treat diseases like Parkinson’s.
Pink neutrophils on a white background.
Mucus-Eating Gut Bacteria May Promote Fever After Cancer Treatment
Alejandra Manjarrez, PhD | Jan 5, 2023 | 3 min read
The expansion of mucus-degraders in the mouse gut—possibly due to poor nutrition—thins the colon’s mucus layer and may weaken defenses against blood-infecting microbes.
Group of cells stained in either blue or green in a black background.
Diabetes Marker Linked to COVID-19 Severity in Mice
Alejandra Manjarrez, PhD | May 16, 2022 | 3 min read
A sugar that’s less abundant in the blood of people with diabetes binds to SARS-CoV-2’s spike protein and disrupts the virus’s ability to fuse with cells.  
Dogs under blanket together stock photo
A Nose by Any Other Name: Tracking the Scent of Tumor Metabolic Waste
Iris Kulbatski, PhD | Apr 11, 2022 | 3 min read
The unique odor profiles of tumors can be used to develop diagnostic sensing tools.
Engineered Bacteria Make Tumors More T Cell-Friendly
Engineered Bacteria Make Tumors More T Cell-Friendly
Aparna Nathan, PhD | Apr 8, 2022 | 5 min read
Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.
white mouse running on a light blue wheel
Tinkering with Gut Microbes Boosts Brain Plasticity in Mice
Sophie Fessl, PhD | Jan 13, 2022 | 4 min read
Intestinal bacteria contribute to the effect of stimulating environments on the brain’s ability to adapt, a study concludes.
Combining metagenomics and metabolomics to unravel microbiome function
Demystifying the Human Gut Microbiome with Multiomics
Metabolon | Dec 23, 2021 | 1 min read
Multiomic approaches identify important metabolites from the gut microbiome.
Measuring Metabolites to Prevent, Diagnose, and Treat Cancer
Niki Spahich, PhD | Jun 11, 2021 | 1 min read
Metabolomics research highlights molecules important for cancer prevention, diagnosis, and treatment.
The Community-Wide Effort to Standardize QA/QC for Metabolomics and Lipidomics
The Scientist | Apr 27, 2021 | 1 min read
Perspectives on the basics and future of QA/QC
Performing Metabolomic and Functional Proteomic Analyses on a Heterogenous Cancer Cell Population
The Scientist Creative Services Team in Collaboration with IsoPlexis | Mar 1, 2021 | 2 min read
A tumor metabolome panel identifies altered cell states that lead to drug tolerance.
major depressive disorder depression microbiome bacteria virus phage bacteriophage metabolite metabolomics
Distinct Microbiome and Metabolites Linked with Depression
Rachael Moeller Gorman | Dec 9, 2020 | 4 min read
The gastrointestinal tracts of people with major depressive disorder harbor a signature composition of viruses, bacteria, and their metabolic products, according to the most comprehensive genomic and metabolomic analysis in depression to date.
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