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The image shows a rendering of a human brain viewed from a lateral perspective with the cerebellum, highlighted in yellow and orange, is situated at the bottom part of the brain where the cerebrum connects with the brainstem.
Revealing the Mutation Behind a Rare Neurological Disease
After 20 years, scientists studying patients with cerebellar degeneration discovered a mutation that disrupts autophagy.
Revealing the Mutation Behind a Rare Neurological Disease
Revealing the Mutation Behind a Rare Neurological Disease

After 20 years, scientists studying patients with cerebellar degeneration discovered a mutation that disrupts autophagy.

After 20 years, scientists studying patients with cerebellar degeneration discovered a mutation that disrupts autophagy.

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neurological disorders

A conceptual illustration of scientists evaluating potential kinase inhibitors.
Leveraging Recombinant Kinases for Drug Discovery Research
The Scientist and Sino Biological | Dec 26, 2024 | 3 min read
As kinase dysfunction underlies many pathological conditions, scientists require high-quality active kinases for their therapeutic development programs.
(Left to right) The first panel is an image of an uneven scale, with the blue male symbol weighing heavier than the red female symbol. The second panel features a mouse with a callout depicting various red and blue lines to represent the estrous cycle. In the third panel, there are images of a mouse, marmoset, and cell culture dish. In the final panel, there is an image of therapeutic pills and gears, representing cognitive function, above a balanced scale. Now the male and female symbols are even.
Infographic: Bridging the Sex Bias Gap
Laura Tran, PhD | Sep 13, 2024 | 3 min read
Researchers challenge a male-dominated field and advocate for more representation of female subjects.
A colorful image of a brain surrounded by outlines of a woman, rodent, and a marmoset. Lines orbit around the brain and are surrounded by stars.
XX Marks the Spot: Addressing Sex Bias in Neuroscience
Laura Tran, PhD | Sep 13, 2024 | 10+ min read
For years, neuroscience research overlooked female subjects, creating a significant bias. Today, researchers actively rebalance the scales with more inclusive and diverse studies.
An illustration of brains on a pink background.
Advancing Neuroscience Research with CyTOF Technology
Standard BioTools | Jul 16, 2024 | 1 min read
Discover how researchers expand their understanding of neurological disorders by using cytometry by time of flight (CyTOF) analysis. 
3D illustration of white neurons with projecting dendrites. 
Stop the Variant, Save the Channel
Shelby Bradford, PhD | Apr 25, 2024 | 4 min read
By using antisense oligonucleotides to inhibit a mutated exon associated with Timothy syndrome mutation, researchers restored neuron function.
Two drawn heads on a blue background with gears in their heads. A red spot on two gears is magnified over one head.
Biological Sex Influences Brain Protein Expression
Shelby Bradford, PhD | Apr 4, 2024 | 3 min read
Neurological disorders often have sex biases, and these differences could be due to altered protein expression in the brain.
Understanding Brain Changes in Response to Extreme Environments
Understanding Brain Changes in Response to Extreme Environments
The Scientist | May 17, 2023 | 1 min read
Steven Jillings and Rachael Seidler will discuss the latest advances in understanding neuroplasticity and dysfunctional brain changes in response to spaceflight.
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