toxicity

Normoxic atmospheric conditions provide excessive oxygen availability, leading to abnormal cell behavior.

Experts discuss reliable high-throughput workflows for PSC-derived cellular screens

An unfolded protein found in human milk shows promise in early clinical trials to treat bladder cancer.

6PPD, a tire preservative, reacts with ozone to produce a compound that the researchers say may be responsible for large die-off events.

In humans, higher oxygen levels during ventilation are tied to an altered bacterial composition in the lungs, and mouse experiments show a causative link.

Screens of hundreds of drug excipients reveal that some can interact with biological targets, contradicting their FDA categorization as inert.

The seven primates came into contact with a dye that was used on their mothers, documents reveal.

Machine learning could be the key to reducing the use of animals in experiments.

After the release of an undercover investigation, Corteva Agrisciences announces it will release 36 beagles for rehoming.

A prototype in-vein device would collect toxic medications before they reach healthy tissues.

Researchers have developed a prototype device to filter excess chemotherapy medication from the bloodstream.

Scrutinizing a company’s study on a widely used pesticide, chlorpyrifos, academic researchers find shortcomings in analyses and public disclosures of results.

Scientists and advocacy groups criticize new guidelines that could exclude some academic studies during toxicity reviews.

Researchers develop a machine-learning tool for toxicity analyses that is more consistent in predicting chemical hazards than assays on animals.

Glyphosate, the active ingredient in Roundup, is designed to be toxic to plants, but scientists observe some untoward effects on animals in the lab. 

Scientists debut a system that can quickly test the toxicity of thousands of compounds in vitro.

A new, two-part TV series to be aired on BBC1 includes video of dolphins playing with toxic puffer fish—possibly to get intoxicated.

Researchers develop a strategy for rendering a toxic drug harmless—until it encounters a pair of enzymes that signals cancer cells are nearby.

Investment in brain research should aim at protecting the brains of the future from harmful environmental pollutants.