cancer biology

The latest group of winning technologies has a little something for everyone—from scientists at the lab bench to those in the clinic and even the classroom.

p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.

Researchers advance the potential of precision medicine with cutting edge sequencing technology.

Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.

A battery that charges itself in salty fluids starves tumors of oxygen, helping improve some drugs treat cancer, a study finds.

Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.

Cohesin mutations cause dysregulations in alternative splicing, contributing to tumor initiation and progression, a study finds. 

DNA sequencing can identify mutations that predict recurrence of renal cell carcinoma and may help low-risk patients avoid unnecessary treatment, a study finds.

Jumping genes are let loose in cancerous cells, with multiple effects on cell health.

Noncoding RNAs and microproteins, once considered genomic noise, are turning out to be critical to the progression of some types of cancer.

The University of Chicago cell biologist is studying how the nutrients available to cancers influence their growth. 

Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.

Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.

Apply today to share your cutting-edge research in The Scientist’s Journal Club.

A particular leucine-ferrying tRNA is more abundant in cancerous cells than healthy ones, and lowering its levels inhibits cancer growth, a study finds.

This year, neuroscience researchers made important discoveries related to how neurodegeneration attacks the human brain, hooked cultured neurons up to machinery to teach them to play a video game, and more.

This year, cancer researchers uncovered a variety of ways that tumors can survive and spread, ranging from damaging their own DNA to exploiting the nearby microenvironment for nutrients.

A high-quality reference genome for this vulnerable feline may help scientists understand why they’re so prone to transitional cell carcinoma in captivity.

The extent to which transcription is higher in tumor cells than in surrounding nontumor cells is associated with bad prognoses in several cancer types.