CRISPR

The latest group of winning technologies has a little something for everyone—from scientists at the lab bench to those in the clinic and even the classroom.

For the past decade, scientists have relied almost exclusively on CRISPR-Cas systems for genome editing. Now, a smaller but equally efficient nuclease is here to compete. 

Lipid nanoparticles deliver CRISPR tools directly to lung stem cells, offering new therapeutic avenues for treating genetic diseases.

The microbiome is a dynamic environment that can give researchers the inside scoop on health and disease.

Discover how scientists produce CRISPR-edited cell populations.

Even as CRISPR-based tools become a lab staple, scientists strive to tackle the associated technological challenges to improve their efficacy and safety.   

Discover how scientists engineer systems constructed from bacterial components to investigate and combat antimicrobial resistance.

Researchers developed a technique, ENGRAM, to keep a running log of the elements that control gene expression in cells. 

In this webinar, Jacob Lamberth will discuss the critical variables and strategies for revolutionizing gene editing experiments.

In this webinar, Jacob Lamberth will discuss the critical variables and strategies for revolutionizing gene editing experiments.

From the laboratory to the table, researchers cooked bioengineered fungi into a tempting patty.

Human cells repair RNA breaks induced by a programmable CRISPR system, paving the way for temporary treatments for genetic diseases.

A tickborne virus uses cholesterol receptors to worm its way into the cell.

A scientist's true legacy lies in the countless researchers they inspire rather than their citation metrics.

By tinkering with branched mRNA structures, scientists lay the groundwork to build better vaccines in the future. 

In this webinar, Douglas Marchuk and Viviana Gradinaru will discuss how scientists can overcome physiological barriers preventing gene therapies from reaching the brain. 

A new approach using two types of recombinases lets scientists insert larger DNA payloads into human pluripotent stem cells faster than ever before. 

Alison Van Eenennaam uses genome-editing technologies to aid beef cattle production and animal welfare.

A new iPSC-derived cellular tool with built-in Cas9 expression enables high efficiency knockout screening for drug target identification and validation.