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A DNA illustration composed of diverse human figures.
AI-Assisted Genome Studies Are Riddled with Errors
Researchers used artificial intelligence in large genomics studies to fill in gaps in patient information and improve predictions, but new research uncovers false positives and misleading correlations.
AI-Assisted Genome Studies Are Riddled with Errors
AI-Assisted Genome Studies Are Riddled with Errors

Researchers used artificial intelligence in large genomics studies to fill in gaps in patient information and improve predictions, but new research uncovers false positives and misleading correlations.

Researchers used artificial intelligence in large genomics studies to fill in gaps in patient information and improve predictions, but new research uncovers false positives and misleading correlations.

Genetics

Crystal structure of adeno-associated virus serotype 3B
A Deep Dive into Viral Vectors for Gene Therapy 
Polyplus and The Scientist | Nov 12, 2024 | 1 min read
As the demand for viral vectors rises in new gene therapy approaches, scientists seek ways to optimize their production.
Single cells rendered in 3D
Capturing Complexity Cell by Cell
10x Genomics | Nov 12, 2024 | 1 min read
With the help of single-cell sequencing, researchers characterize biological complexity more fully across a multitude of applications.
A 3D scientific illustration of two X chromosomes
Genetic Signals Linked to X Chromosome Loss Later in Life
Claudia Lopez-Lloreda, PhD | Nov 12, 2024 | 3 min read
Loss of the X chromosome increases with age and may have implications for health and disease risk.
Short strands of RNA floating on a blue background
Gene Silencing with RNA Interference
Rebecca Roberts, PhD | Nov 11, 2024 | 5 min read
Gene knockdown using RNAi enables gene function studies, with applications from pest control to biotherapeutics.
Solving Sample Preparation Challenges Across Diverse Tissue Types
Solving Sample Preparation Challenges Across Diverse Tissue Types
The Scientist Staff | Nov 11, 2024 | 1 min read
In this webinar, Caleb Proctor will tackle nucleic acid extraction complexities, sharing a streamlined pathway for obtaining high-quality and high-quantity results.
Image of Caenorhabditis elegans against a black background.
Worms’ Nose for Danger Helps Ward Off Pathogens 
Laura Tran, PhD | Nov 7, 2024 | 3 min read
Nematodes can sniff out trouble, kicking off a mitochondrial defense in the gut to fend off bacterial invaders.
Close-up of 8-channel pipette adding solution to a multi-well plate for transfection.
Channeling Transfection Success and Enhanced Electroporation
Thermo Fisher Scientific | Nov 6, 2024 | 1 min read
A new eight-channel pipette reduces experimental time and effort, providing researchers with more efficient transfection workflows.
Exploring How Sequencing and Omics are Shaping Disease Research
Exploring How Sequencing and Omics are Shaping Disease Research
The Scientist Staff | Nov 6, 2024 | 2 min read
In this symposium, an expert panel will discuss how sequencing and omics technologies enable unprecedented exploration of health and disease, from genetic disorders to cancer. 
Newborn heel prick test for genetic screening
Transforming Molecular Workflows for Newborn Screening
The Scientist and Revvity | Nov 5, 2024 | 1 min read
New PCR-based approaches simplify molecular testing for health issues in infants, making diagnostic approaches more accessible across laboratories.
Illustration of a pink brain in a silhouette on a background with brainwaves. 
Sleep Disruptions and Impaired Muscle Control in Ataxia May Share a Culprit
Shelby Bradford, PhD | Nov 5, 2024 | 4 min read
Dysfunctional neurons in the cerebellum, a brain region that controls motor functions, reduced REM sleep in mice.
Fluorescent multicolored waveform lines on a black background.
Next-Generation PCR Instruments Boost Workflows 
The Scientist Staff | Nov 1, 2024 | 2 min read
Modern, intuitive, and reliable thermal cyclers excel at optimizing sequencing, cloning, and genotyping throughput.
A photo of blood vials arranged in rows.
Automating Liquid Biopsy: Unleashing New Potential in Diagnostics
Tecan | Oct 30, 2024 | 1 min read
Discover how automation increases the efficiency and reliability of blood-based liquid biopsy assays.
An artistic interpretation of CRISPR genome editing showing the cutting and changing of DNA segments.
A Small Genome Editing Nuclease Packs a Big Punch
Sahana Sitaraman, PhD | Oct 30, 2024 | 4 min read
For the past decade, scientists have relied almost exclusively on CRISPR-Cas systems for genome editing. Now, a smaller but equally efficient nuclease is here to compete. 
A team of scientists engaged in protein engineering experiments in a laboratory, showcasing advanced research techniques.
Insights Into Protein Engineering: Methods and Applications
Priyom Bose, PhD | Oct 29, 2024 | 7 min read
Synthetic biologists modify naturally occurring amino acid sequences to engineer proteins and enzymes for specific applications.
Image of blood in a test tube with the four base pairs of DNA in the background.
A Novel Polymerase Reduces Stutter in Forensic DNA Analysis
Laura Tran, PhD | Oct 28, 2024 | 4 min read
A breakthrough enzyme aims to resolve a persistent DNA artifact that has challenged forensic analysis for decades.
The two sections show an oval-shaped structure, some of which is red in color. The red-colored structure is larger in the image above.
Fathers’ Gut Bacteria Impact Offspring Health
Sneha Khedkar | Oct 25, 2024 | 4 min read
Gut microbiome disruption in male mice increases disease risk in offspring, indicating that preconception paternal health status can affect the next generation.
Illustration of a small microRNA in blue with additional microRNAs in the background. 
From Worm Anomaly to Nobel Prize: microRNAs Show Macro Impact
Danielle Gerhard, PhD | Oct 21, 2024 | 5 min read
Discovered 30 years ago, microRNAs are increasingly recognized as important regulators of cell physiology and human disease.
Cartoon humans standing on a DNA profile.
A Geneticist's Journey From a Lupus Victory to a Murder Case Verdict
Danielle Gerhard, PhD | Oct 21, 2024 | 10+ min read
Carola Vinuesa’s research has illuminated the genetics of lupus and helped to exonerate a mother falsely accused of murdering her four children. 
Test tubes containing urine samples
Achieving Better Test Sensitivity for Cancer Liquid Biopsies
DNA Genotek Inc. | Oct 18, 2024 | 1 min read
First-void urine has emerged as a promising sample type for cancer diagnostic test development.
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