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Image of an axon, with a callout box highlighting a portion of the cell membrane. It depicts three different electrodes and ion channels along the membrane.
What’s the Difference Between a Voltage Clamp and a Current Clamp?
Laura Tran, PhD | Dec 2, 2024 | 2 min read
Depending on the “clamped” parameter, patch clamp configurations probe different aspects of a cell's electrical activity.
A photo of a 96-well microplate showcasing serial dilutions of purple dye solution.
Achieving Consistency in Serial Dilutions
The Scientist Staff | Dec 2, 2024 | 2 min read
Researchers ensure the success of their serial dilution-based assays by using optimized protocols and advanced liquid handling tools.
A young child holding her bruised knee.
A Beneficial Bacterium Helps Wounds Heal
Sneha Khedkar | Dec 2, 2024 | 5 min read
A bacterium found in the wound microbiome can accelerate healing, highlighting the potential for microbiota-based wound therapies.
A 3D rendered model of a glutamic acid molecule with other organic molecules floating around it.
Protein Makeover with Custom Amino Acids
Laura Tran, PhD | Dec 2, 2024 | 2 min read
With a plug-and-play strategy, researchers engineer proteins with new functions.
<em>The Scientist</em> December crossword puzzle
Science Crossword Puzzle
Stella Zawistowski | Dec 2, 2024 | 1 min read
Put on your thinking cap, and take on this fun challenge.
A bowl filled with various nuts, beans, seeds, avocado, oats, cheeses, and meat, is arranged by color to form a yin-yang symbol. The background is filled with cartoon images of cells.
A Keto Diet Could Enhance Cancer Drug Effectiveness
Paige Nicklas | Nov 29, 2024 | 4 min read
In mice, a ketogenic diet remodeled the translatome of pancreatic cancer cells, rendering them vulnerable to targeted therapy.
An illustration showing a DNA strand and a cancer cell.&nbsp;
How Some Cancer Cells Survive Chemotherapy
Sahana Sitaraman, PhD | Nov 26, 2024 | 4 min read
Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells overcome this effect and resist death. 
Image of a showerhead with running water. There is a soap dispenser and toothbrush on a wire shelf in the shower.
A Viral Investigation of Bathroom Biomes
Laura Tran, PhD | Nov 26, 2024 | 4 min read
Hidden on toothbrushes and showerheads, bacteriophages reveal a viral ecosystem and its potential to create healthier living spaces.
An illustration of mRNA molecules.
Probing the Structure of mRNA Molecules
Shimadzu | Nov 25, 2024 | 1 min read
Learn how scientists examine mRNA quality using an easy-to-operate LC-MS system.
An orange Pseudomonas aeruginosa bacterium with white flagella on a blue background.
Pseudomonas Bacteria Escape Immunity by Disrupting Energy Production in Macrophages
Kamal Nahas, PhD | Nov 25, 2024 | 4 min read
Pseudomonas infections are tough to treat, but a new study reveals a chemical they use to subdue macrophages, suggesting new therapeutic avenues.
A photograph of a man sleeping on a couch next to a plate with a poultry leg on it.
Why Does Thanksgiving Dinner Make Some People Sleepy?
Shelby Bradford, PhD | Nov 25, 2024 | 4 min read
Urban myths cry turkey, but the science behind why Thanksgiving feasts induce sleep suggests otherwise.
A brittle star with its thin, serpent-like arms against a black background.
Diving Into the Brittle Star Genome to Understand the Evolution of Regeneration
Sneha Khedkar | Nov 22, 2024 | 4 min read
The sequenced genome of the brittle star revealed unique gene arrangements and provides insights into ancient genes involved in limb regeneration.
A pink and yellow protein held together by a gray circle pull a piece of blue DNA into a loop.
Combining Bacterial Systems Offers a New Approach to Gene Regulation
Shelby Bradford, PhD | Nov 22, 2024 | 4 min read
Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression.
A fruit fly (Drosophila melanogaster) sitting on a green grass blade with a green background.
How the Fly Brain Knows When to Release Insulin
Sneha Khedkar | Nov 21, 2024 | 4 min read
An enzyme synthesized in the fly gut travels to the brain, where it induces insulin-like peptide secretion.
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