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A small furry shrew pokes its head out from a pile of vegetation.
Gene Expression Shifts as Shrews Shrink and Regrow Their Brains
Transcriptomic studies of the shrew’s remarkably plastic brain could provide new insights into neurodegenerative diseases.
Gene Expression Shifts as Shrews Shrink and Regrow Their Brains
Gene Expression Shifts as Shrews Shrink and Regrow Their Brains

Transcriptomic studies of the shrew’s remarkably plastic brain could provide new insights into neurodegenerative diseases.

Transcriptomic studies of the shrew’s remarkably plastic brain could provide new insights into neurodegenerative diseases.

News

A cartoon of pills and bacteria along the human intestine.
An Antibiotic That Distinguishes Friend from Foe
Sneha Khedkar | Nov 19, 2024 | 4 min read
A novel compound targets an essential transport system found only in disease-causing bacteria, leaving commensal bacteria unharmed. 
Multiple panels of a magnetic resonance imaging brain scan.
Blocking Scar Formation Prevents Glioblastoma Recurrence
Rebecca Roberts, PhD | Nov 18, 2024 | 5 min read
A combination of three therapies prevented scar tissue and stopped glioblastoma in its tracks in mice.
An illustration showing reduction in muscle mass and weight from cachexia.
The Neural Circuitry Driving Cancer-Related Wasting Disease
Sahana Sitaraman, PhD | Nov 18, 2024 | 4 min read
In mice, dampening the activity of area postrema neurons diminished cancer-induced muscle and fat loss and increased lifespan.
Nathalie Fuentes, a senior scientist at AstraZeneca, is shown completing two of her roles: on the left, she prepares regulatory paperwork for a new drug, while on the right, she documents information from stability testing a new drug.
The Secrets of Securing a Senior Scientist Role in an Industry
Shelby Bradford, PhD | Nov 15, 2024 | 5 min read
Nathalie Fuentes shared her experience of landing a unicorn position in a pharmaceutical company after a postdoctoral fellowship.
A herd of elephants is walking in a river in a forest.
Elephant Deaths Trigger a Kodo-Millet Fungus Investigation in India
Sneha Khedkar | Nov 14, 2024 | 4 min read
When multiple elephants were found dead in a national park in India, microbiologists turned to investigate their prime suspect: fungi. 
Image of a cone snail, Conus geographus underwater.
A Sea Snail Toxin Could Inspire New Diabetes Drugs
Laura Tran, PhD | Nov 14, 2024 | 5 min read
Sea snails stun their prey with toxins that mimic glucose-regulating hormones.
Chickens on a farm.
A Wastewater Surveillance Program Sounds the Alarm on Avian Influenza
Deanna MacNeil, PhD | Nov 14, 2024 | 6 min read
Born from the COVID-19 pandemic, a viral-agnostic approach blends sequencing research and public health to get ahead of bird flu transmission.
A DNA illustration composed of diverse human figures.
AI-Assisted Genome Studies Are Riddled with Errors
Sahana Sitaraman, PhD | Nov 13, 2024 | 3 min read
Researchers used artificial intelligence in large genomics studies to fill in gaps in patient information and improve predictions, but new research uncovers false positives and misleading correlations.
Multiple green and blue protein structures on a black background
How Stem Cells Stay Young
Rohini Subrahmanyam, PhD | Nov 13, 2024 | 4 min read
Bone marrow stem cells defy typical aging, and it may be because they express the right proteins.
A doctor holds a model of the female reproductive system.
Modeling the Human Cervix on a USB-Sized Chip
Sneha Khedkar | Nov 13, 2024 | 4 min read
Microfluidic chips that mimic the complex human cervical environment provide a platform to study the reproductive tract and associated infections like bacterial vaginosis.
Photo of a brown soy pulp patty sitting in a cream sauce alongside a cucumber and tomato salad and baked yams.
How Can Fungi Address the Global Food Waste Problem?
Danielle Gerhard, PhD | Nov 12, 2024 | 8 min read
Scientists are reimagining the food system, turning to fungal fermentation as a sustainable method for transforming food byproducts into tasty treats.
A 3D scientific illustration of two X chromosomes
Genetic Signals Linked to X Chromosome Loss Later in Life
Claudia Lopez-Lloreda, PhD | Nov 12, 2024 | 3 min read
Loss of the X chromosome increases with age and may have implications for health and disease risk.
3D illustration of white Candida albicans yeast cells growing against host tissue.
A Fungal Messenger Impairs Immune Cell Function
Shelby Bradford, PhD | Nov 8, 2024 | 3 min read
Farnesol, a fungal signaling molecule, alters lipid synthesis in dendritic cells, causing mitochondrial dysfunction and decreased inflammatory responding.
A golden retriever shakes off water on a sunny lawn.
What Drives the "Wet Dog Shakes" Reflex in Furry Animals?
Hannah Thomasy, PhD | Nov 7, 2024 | 3 min read
Scientists identified the mechanoreceptor that triggers the distinctive shake-off behavior observed in mice when they become wet.
Image of Caenorhabditis elegans against a black background.
Worms’ Nose for Danger Helps Ward Off Pathogens 
Laura Tran, PhD | Nov 7, 2024 | 3 min read
Nematodes can sniff out trouble, kicking off a mitochondrial defense in the gut to fend off bacterial invaders.
3D illustration of dark, oval parasites invading translucent host cells with blue nuclei.
Live Imaging Intracellular Parasites Reveals Changes to Host Metabolism
Shelby Bradford, PhD | Nov 6, 2024 | 4 min read
Researchers found that Toxoplasma gondii increased the host cell’s metabolic activity, offering insights into potential treatment strategies.
Illustration of a pink brain in a silhouette on a background with brainwaves. 
Sleep Disruptions and Impaired Muscle Control in Ataxia May Share a Culprit
Shelby Bradford, PhD | Nov 5, 2024 | 4 min read
Dysfunctional neurons in the cerebellum, a brain region that controls motor functions, reduced REM sleep in mice.
Bluish-grey circles of fuzzy mold grow in a Petri dish.
How a Moldy Cantaloupe Took Fleming’s Penicillin from Discovery to Mass Production
Hannah Thomasy, PhD | Nov 4, 2024 | 10+ min read
Alexander Fleming’s 1928 discovery of a mold with antibacterial properties was only the first serendipitous event on the long road to penicillin as a life-saving drug.
An illustration of seven T cells (in seafoam green) attack a cancer cell (in pink).
Meet Cyclone: A Monitoring Tool That Watches for Waves of Immune Response
Rashmi Shivni | Nov 1, 2024 | 4 min read
A new algorithm detects when immunotherapies create surges of T cell responses in melanoma patients.
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